Medical College of Wisconsin
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John R. McGuire MD

Professor

Institution: Medical College of Wisconsin
Department: Physical Medicine and Rehabilitation

Member of the Wisconsin Institute of NeuroScience (WINS)

View Curriculum Vitae

Research Areas of Interest

  • Humans

    • Publications (56)

  • The Feasibility and User Experience of a Program of Progressive Cued Activity to Promote Functional Upper Limb Activity in the Inpatient Rehabilitation Setting with Follow-Up at Home (Bassindale K, Golus S, Horder J, Winkoski M, Sytsma M, Morelli WA, Casadio M, McGuire J, Scheidt RA) Applied Sciences Switzerland March 2025;15(6) SCOPUS ID: 2-s2.0-105000950122 03/01/2025       1 Citation
  • Utility and usability of a wearable system and progressive-challenge cued exercise program for encouraging use of the more involved arm at-home after stroke-a feasibility study with case reports. (Horder J, Mrotek LA, Casadio M, Bassindale KD, McGuire J, Scheidt RA) J Neuroeng Rehabil 2024 Apr 30;21(1):66 PMID: 38685012 PMCID: PMC11059679 SCOPUS ID: 2-s2.0-85191859704 04/30/2024       8 Citations
  • Spatial mapping of posture-dependent resistance to passive displacement of the hypertonic arm post-stroke. (Kanade-Mehta P, Bengtson M, Stoeckmann T, McGuire J, Ghez C, Scheidt RA) J Neuroeng Rehabil 2023 Dec 01;20(1):163 PMID: 38041164 PMCID: PMC10693118 SCOPUS ID: 2-s2.0-85178172739 12/02/2023       3 Citations
  • The combo meal: Combined treatments for spasticity management (McGuire J) Handbook of Spasticity A Practical Approach to Management 15 September 2023:317-325 SCOPUS ID: 2-s2.0-85168257200 09/15/2023    
  • Changes in Cortical Activity in Stroke Survivors Undergoing Botulinum Neurotoxin Therapy for Treatment of Focal Spasticity. (Vinehout K, Tynes K, Sotelo MR, Hyngstrom AS, McGuire JR, Schmit BD) Front Rehabil Sci 2021;2:735819 PMID: 36188774 PMCID: PMC9397708 SCOPUS ID: 2-s2.0-85174971178 10/04/2022       3 Citations
  • Intrathecal Baclofen Therapy in Patients With Multiple Sclerosis: Improved Outcomes and Reduced Costs Through Identification of Catheter Malfunction. (Nelson MES, McGuire JR) Neuromodulation 2019 Oct;22(7):839-842 PMID: 31157471 SCOPUS ID: 2-s2.0-85067086405 06/04/2019       3 Citations
  • The Arm Movement Detection (AMD) test: a fast robotic test of proprioceptive acuity in the arm. (Mrotek LA, Bengtson M, Stoeckmann T, Botzer L, Ghez CP, McGuire J, Scheidt RA) J Neuroeng Rehabil 2017 Jun 28;14(1):64 PMID: 28659156 PMCID: PMC5490232 SCOPUS ID: 2-s2.0-85021390387 07/01/2017       12 Citations
  • OnabotulinumtoxinA for Lower Limb Spasticity: Guidance From a Delphi Panel Approach. (Esquenazi A, Alfaro A, Ayyoub Z, Charles D, Dashtipour K, Graham GD, McGuire JR, Odderson IR, Patel AT, Simpson DM) PM R 2017 Oct;9(10):960-968 PMID: 28286053 SCOPUS ID: 2-s2.0-85017519310 03/14/2017       46 Citations
  • Safety and efficacy of incobotulinumtoxinA doses up to 800 U in limb spasticity: The TOWER study. (Wissel J, Bensmail D, Ferreira JJ, Molteni F, Satkunam L, Moraleda S, Rekand T, McGuire J, Scheschonka A, Flatau-Baqué B, Simon O, Rochford ET, Dressler D, Simpson DM, TOWER study investigators) Neurology 2017 Apr 04;88(14):1321-1328 PMID: 28283596 PMCID: PMC5379931 SCOPUS ID: 2-s2.0-85017152445 03/12/2017       114 Citations
  • Should Ultrasound Be Used Routinely to Guide Botulinum Toxin Injections for Spasticity? (McGuire J, Heath K, O'Dell MW) PM R 2016 Oct;8(10):1004-1010 PMID: 27769363 SCOPUS ID: 2-s2.0-84992410781 10/23/2016       2 Citations
  • Assessment of Kinematics and Electromyography Following Arthroscopic Single-Tendon Rotator Cuff Repair. (Fritz JM, Inawat RR, Slavens BA, McGuire JR, Ziegler DW, Tarima SS, Grindel SI, Harris GF) PM R 2017 May;9(5):464-476 PMID: 27639653 SCOPUS ID: 2-s2.0-84991205365 10/19/2016       13 Citations
  • Poster 371 Escalating Doses of IncobotulinumtoxinA (400-800U) Are Well Tolerated and Lead to Increasing Improvements in Disability Due to Multifocal Upper- and Lower-Limb Spasticity. (Wissel J, Bensmail D, McGuire JR, Rubin BS, Scheschonka A, Simon O, Simpson DM) PM R 2016 Sep;8(9S):S282 PMID: 27673123 09/28/2016    
  • Poster 354 OnabotulinumtoxinA to Treat Common Postures in Post-Stroke Lower Limb Spasticity: Identification of a Treatment Paradigm. (Esquenazi A, Dashtipour K, Alfaro A, Ayyoub Z, Charles D, Graham GD, McGuire JR, Odderson IR, Patel AT, Simpson DM) PM R 2016 Sep;8(9S):S276 PMID: 27673106 09/28/2016    
  • Best Practices for Intrathecal Baclofen Therapy: Patient Selection. (Saulino M, Ivanhoe CB, McGuire JR, Ridley B, Shilt JS, Boster AL) Neuromodulation 2016 Aug;19(6):607-15 PMID: 27434197 SCOPUS ID: 2-s2.0-84981749596 07/20/2016       74 Citations
  • OnabotulinumtoxinA Injection for Poststroke Upper-Limb Spasticity: Guidance for Early Injectors From a Delphi Panel Process. (Simpson DM, Patel AT, Alfaro A, Ayyoub Z, Charles D, Dashtipour K, Esquenazi A, Graham GD, McGuire JR, Odderson I) PM R 2017 Feb;9(2):136-148 PMID: 27346090 SCOPUS ID: 2-s2.0-85008423011 06/28/2016       35 Citations
  • Intrathecal Baclofen Dosing Regimens: A Retrospective Chart Review. (Clearfield JS, Nelson ME, McGuire J, Rein LE, Tarima S) Neuromodulation 2016 Aug;19(6):642-9 PMID: 26517855 SCOPUS ID: 2-s2.0-84981747156 10/31/2015       16 Citations
  • Poststroke spasticity management. (Francisco GE, McGuire JR) Stroke 2012 Nov;43(11):3132-6 PMID: 22984012 SCOPUS ID: 2-s2.0-84868193042 09/18/2012       140 Citations
  • Quantifying learned non-use after stroke using unilateral and bilateral steering tasks. (Johnson M, Paranjape R, Strachota E, Tchekanov G, McGuire J) IEEE Int Conf Rehabil Robot 2011;2011:5975457 PMID: 22275655 SCOPUS ID: 2-s2.0-80055044166 01/26/2012       11 Citations
  • Bilateral assessment of functional tasks for robot-assisted therapy applications. (Johnson MJ, Wang S, Bai P, Strachota E, Tchekanov G, Melbye J, McGuire J) Med Biol Eng Comput 2011 Oct;49(10):1157-71 PMID: 21881901 PMCID: PMC3204422 SCOPUS ID: 2-s2.0-84879790320 09/02/2011       24 Citations
  • Stroke. Foreword. (McGuire JR) Top Stroke Rehabil 2011;18(3):v PMID: 21702214 SCOPUS ID: 2-s2.0-79960111643 06/28/2011    
  • The underutilization of intrathecal baclofen in poststroke spasticity. (Dvorak EM, Ketchum NC, McGuire JR) Top Stroke Rehabil 2011;18(3):195-202 PMID: 21642057 SCOPUS ID: 2-s2.0-79958084023 06/07/2011       29 Citations
  • Effect of ankle orientation on heel loading and knee stability for post-stroke individuals wearing ankle-foot orthoses. (Silver-Thorn B, Herrmann A, Current T, McGuire J) Prosthet Orthot Int 2011 Jun;35(2):150-62 PMID: 21515899 SCOPUS ID: 2-s2.0-82255172082 04/26/2011       26 Citations
  • Incidence and identification of intrathecal baclofen catheter malfunction. (Dvorak EM, McGuire JR, Nelson ME) PM R 2010 Aug;2(8):751-6 PMID: 20598957 SCOPUS ID: 2-s2.0-77955657000 07/06/2010       45 Citations
  • Evaluation of the TheraDrive system for robot/computer assisted motivating rehabilitation after stroke. (Ruparel R, Johnson MJ, Strachota E, McGuire J, Tchekanov G) Annu Int Conf IEEE Eng Med Biol Soc 2009;2009:811-4 PMID: 19963475 SCOPUS ID: 2-s2.0-77951012966 12/08/2009       15 Citations
  • Design and validation of low-cost assistive glove for hand assessment and therapy during activity of daily living-focused robotic stroke therapy. (Nathan DE, Johnson MJ, McGuire JR) J Rehabil Res Dev 2009;46(5):587-602 PMID: 19882493 PMCID: PMC8010363 SCOPUS ID: 2-s2.0-70350437635 11/03/2009       46 Citations
  • Spastic hypertonia and movement disorders: pathophysiology, clinical presentation, and quantification. (Sheean G, McGuire JR) PM R 2009 Sep;1(9):827-33 PMID: 19769916 SCOPUS ID: 2-s2.0-70349227630 09/23/2009       168 Citations
  • Multijoint reflex responses to constant-velocity volitional movements of the stroke elbow. (Sangani SG, Starsky AJ, McGuire JR, Schmit BD) J Neurophysiol 2009 Sep;102(3):1398-410 PMID: 19553478 SCOPUS ID: 2-s2.0-70349299884 06/26/2009       11 Citations
  • Feasibility of integrating FES grasp assistance with a task- oriented robot-assisted therapy environment: A case study (Nathan DE, Johnson MJ, McGuire J) Proceedings of the 2nd Biennial IEEE Ras EMBS International Conference on Biomedical Robotics and Biomechatronics Biorob 2008 2008:807-812 SCOPUS ID: 2-s2.0-63049102819 12/01/2008       16 Citations
  • Multijoint reflexes of the stroke arm: neural coupling of the elbow and shoulder. (Sangani SG, Starsky AJ, McGuire JR, Schmit BD) Muscle Nerve 2007 Nov;36(5):694-703 PMID: 17628498 SCOPUS ID: 2-s2.0-35448999362 07/14/2007       30 Citations
  • Quantification of reaching during stroke rehabilitation using unique upper extremity kinematic model. (Hingtgen BA, McGuire JR, Wang M, Harris GF) Conf Proc IEEE Eng Med Biol Soc 2004;2004:4916-9 PMID: 17271415 02/03/2007    
  • Electrode pressure application and measurement system during CMAP studies: preliminary results. (Ezenwa BN, McGuire JR) Conf Proc IEEE Eng Med Biol Soc 2004;2004:4733-6 PMID: 17271366 02/03/2007    
  • Intrathecal baclofen management of poststroke spastic hypertonia: implications for function and quality of life. (Ivanhoe CB, Francisco GE, McGuire JR, Subramanian T, Grissom SP) Arch Phys Med Rehabil 2006 Nov;87(11):1509-15 PMID: 17084128 SCOPUS ID: 2-s2.0-33750479523 11/07/2006       67 Citations
  • Consensus statement on the use of botulinum neurotoxin to treat spasticity in adults (Davis TL, Brodsky MA, Carter VA, DiFazio M, Frishberg B, Lai EC, McGuire J, Meyer DP, Ostrem JL, Sarwar AI, White K) P and T November 2006;31(11):666-682 SCOPUS ID: 2-s2.0-33845216007 11/01/2006       11 Citations
  • An upper extremity kinematic model for evaluation of hemiparetic stroke. (Hingtgen B, McGuire JR, Wang M, Harris GF) J Biomech 2006;39(4):681-8 PMID: 16439237 SCOPUS ID: 2-s2.0-31344466554 01/28/2006       121 Citations
  • Quantitative assessment of upper extremity stroke rehabilitation following distal extremity botulinum toxin a injection (Hingtgen BA, McGuire JR, Wang M, Harris GF) Proceedings of the 2005 Summer Bioengineering Conference 2005;2005:463-464 SCOPUS ID: 2-s2.0-33646597731 12/01/2005    
  • Kinematic implications of learned non-use for robotic therapy (Johnson MJ, Wisneski K, Hermsen A, Smith RQ, Walton T, Hingtgen B, McGuire JR, Harris GF) Proceedings of the 2005 IEEE 9th International Conference on Rehabilitation Robotics 2005;2005:70-73 SCOPUS ID: 2-s2.0-33745804513 12/01/2005       2 Citations
  • Reliability of biomechanical spasticity measurements at the elbow of people poststroke. (Starsky AJ, Sangani SG, McGuire JR, Logan B, Schmit BD) Arch Phys Med Rehabil 2005 Aug;86(8):1648-54 PMID: 16084821 SCOPUS ID: 2-s2.0-23644447247 08/09/2005       73 Citations
  • Electrode pressure application and measurement system during CMAP studies: Preliminary results (Ezenwa BN, McGuire JR) Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings 2004;26 VII:4733-4736 SCOPUS ID: 2-s2.0-11144325748 12/01/2004    
  • Quantification of reaching during stroke rehabilitation using a unique upper extremity kinematic model (Hingtgen BA, McGuire JR, Wang M, Harris GF) Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings 2004;26 VII:4916-4919 SCOPUS ID: 2-s2.0-11144345002 12/01/2004       8 Citations
  • Design and Validation of an Upper Extremity Kinematic Model for Application in Stroke Rehabilitation (Hingtgen BA, McGuire JR, Wang M, Harris GF) Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings 2003;2:1682-1685 SCOPUS ID: 2-s2.0-1542331585 12/01/2003       12 Citations
  • Biomechanical Study and Objective Evaluation of Muscle Co-Contraction Following Chemodenervation (Myers KA, McGuire JR, Long JT, Harris GF) Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings 2003;2:1815-1818 SCOPUS ID: 2-s2.0-1542301585 12/01/2003    
  • Effective use of chemodenervation and chemical neurolysis in the management of poststroke spasticity. (McGuire JR) Top Stroke Rehabil 2001;8(1):47-55 PMID: 14523751 SCOPUS ID: 2-s2.0-0035010579 10/03/2003       11 Citations
  • Maximizing extraction of botulinum toxin type A from vials. (Dykstra DD, Wieting JM, McGuire J, Kowalkowski T) Arch Phys Med Rehabil 2002 Nov;83(11):1638-40 PMID: 12422338 SCOPUS ID: 2-s2.0-0036847021 11/08/2002       6 Citations
  • Upper extremity motion assessment in adult ischemic stroke patients: A 3-D kinematic model (Van Bogart J, McGuire J, Harris GF) Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings 2001;2:1190-1192 SCOPUS ID: 2-s2.0-1842451139 01/01/2001       2 Citations
  • The prevention and management of complications after stroke. (McGuire JR, Harvey RL) Phys Med Rehabil Clin N Am 1999 Nov;10(4):857-74, ix PMID: 10573712 SCOPUS ID: 2-s2.0-0032748834 11/26/1999       26 Citations
  • Reorganization of flexion reflexes in the upper extremity of hemiparetic subjects. (Dewald JP, Beer RF, Given JD, McGuire JR, Rymer WZ) Muscle Nerve 1999 Sep;22(9):1209-21 PMID: 10454716 SCOPUS ID: 2-s2.0-0032841654 08/24/1999       50 Citations
  • Beyond Ashworth. Electrophysiologic quantification of spasticity. (Sehgal N, McGuire JR) Phys Med Rehabil Clin N Am 1998 Nov;9(4):949-79, ix PMID: 9894105 SCOPUS ID: 2-s2.0-0031793988 01/20/1999       68 Citations
  • Stroke rehabilitation: clinical predictors of resource utilization. (Harvey RL, Roth EJ, Heinemann AW, Lovell LL, McGuire JR, Diaz S) Arch Phys Med Rehabil 1998 Nov;79(11):1349-55 PMID: 9821892 SCOPUS ID: 2-s2.0-0031727796 11/20/1998       63 Citations
  • Impairment and disability: their relation during stroke rehabilitation. (Roth EJ, Heinemann AW, Lovell LL, Harvey RL, McGuire JR, Diaz S) Arch Phys Med Rehabil 1998 Mar;79(3):329-35 PMID: 9523787 SCOPUS ID: 2-s2.0-0031958277 04/02/1998       134 Citations
  • Effective collaboration between physician and occupational therapist in the management of upper limb spasticity after stroke (Scanlan SM, McGuire J) Topics in Stroke Rehabilitation 1998;4(4):1-13 SCOPUS ID: 2-s2.0-0031910839 03/24/1998       3 Citations
  • Erratum: (Muscle and Nerve (1997) 6 (S92-S120)) (Gracies JM, Nance P, Elovic E, McGuire J, Simpson DM) Muscle and Nerve 1998;21(7):983 SCOPUS ID: 2-s2.0-0031745142 01/01/1998    
  • Traditional pharmacological treatments for spasticity part II: General and regional treatments (Gracies JM, Elovic E, McGuire J, Simpson D) Muscle and Nerve 1997;20(SUPPL. 6):S92-S120 SCOPUS ID: 2-s2.0-0002738203 12/01/1997       75 Citations
  • Spasticity, etiology, evaluation, management, and the role of botulinum toxin type A (Brin MF, Albany K, Alexander D, Cava T, Chambers HG, Childers MK, Comella C, Elovic E, Esquenazi A, Gormley J, Gracies JM, Ivanhoe C, Jankovic J, Leach J, McGuire J, Mayer NH, O'Brien CF, Pierson SH, Russman BS, Simpson DM, Tilton A, Yablon SA) Muscle and Nerve 1997;20(SUPPL. 6):S1-S223 SCOPUS ID: 2-s2.0-0031453617 12/01/1997       10 Citations
  • Measurement properties of the NIH Stroke Scale during acute rehabilitation. (Heinemann AW, Harvey RL, McGuire JR, Ingberman D, Lovell L, Semik P, Roth EJ) Stroke 1997 Jun;28(6):1174-80 PMID: 9183346 SCOPUS ID: 2-s2.0-0030914503 06/01/1997       37 Citations
  • Traditional pharmacological treatments for spasticity. Part I: Local treatments. (Gracies JM, Elovic E, McGuire J, Simpson DM) Muscle Nerve Suppl 1997;6:S61-91 PMID: 9826983 SCOPUS ID: 2-s2.0-0002738202 01/01/1997       158 Citations
  • Central Poststroke Pain. (Roth EJ, McGuire JR) Top Stroke Rehabil 1996 Jan;2(4):77-84 PMID: 27620156 SCOPUS ID: 2-s2.0-0030053126 01/01/1996    
    • Last update: 04/08/2025