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Martin St. Maurice PhD
Associate Professor
Institution:
Marquette University
Department:
Biology
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Publications (22)
Synthesis and Evaluation of 1,3-Disubstituted Imidazolidine-2,4,5-triones as Inhibitors of Pyruvate Carboxylase.
(Schneider NO, Gilreath K, Henriksen NM, Donaldson WA, Chaudhury S, St Maurice M)
ACS Med Chem Lett
2024 Jul 11;15(7):1088-1093 PMID: 39015262 PMCID: PMC11247459 SCOPUS ID: 2-s2.0-85197491396 07/17/2024
1 Citation
Synthesis and Evaluation of 5-(Heteroarylmethylene)hydantoins as Glycogen Synthase Kinase-3β Inhibitors.
(Schneider NO, Gilreath K, Burkett DJ, St Maurice M, Donaldson WA)
Pharmaceuticals (Basel)
2024 Apr 29;17(5) PMID: 38794140 PMCID: PMC11123921 SCOPUS ID: 2-s2.0-85194104398 05/25/2024
Allosteric Site at the Biotin Carboxylase Dimer Interface Mediates Activation and Inhibition in
Staphylococcus aureus
Pyruvate Carboxylase.
(Laseke AJ, Boram TJ, Schneider NO, Lohman JR, St Maurice M)
Biochemistry
2023 Sep 05;62(17):2632-2644 PMID: 37603581 PMCID: PMC10693930 SCOPUS ID: 2-s2.0-85169846949 08/21/2023
2 Citations
Conformational Selection Governs Carrier Domain Positioning in
Staphylococcus aureus
Pyruvate Carboxylase.
(Hakala JH, Laseke AJ, Koza AL, St Maurice M)
Biochemistry
2022 Sep 06;61(17):1824-1835 PMID: 35943735 PMCID: PMC11451948 SCOPUS ID: 2-s2.0-85136471117 08/10/2022
2 Citations
Slow-Onset, Potent Inhibition of Mandelate Racemase by 2-Formylphenylboronic Acid. An Unexpected Adduct Clasps the Catalytic Machinery.
(Douglas CD, Grandinetti L, Easton NM, Kuehm OP, Hayden JA, Hamilton MC, St Maurice M, Bearne SL)
Biochemistry
2021 Aug 02 PMID: 34339165 SCOPUS ID: 2-s2.0-85113701872 08/03/2021
5 Citations
Channeling a complex question.
(St Maurice M)
Nat Chem Biol
2020 Sep;16(9):935-937 PMID: 32812007 SCOPUS ID: 2-s2.0-85089518021 08/20/2020
1 Citation
Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center.
(Sharma AN, Grandinetti L, Johnson ER, St Maurice M, Bearne SL)
Biochemistry
2020 Aug 25;59(33):3026-3037 PMID: 32786399 SCOPUS ID: 2-s2.0-85089922806 08/14/2020
8 Citations
Evaluation of α-hydroxycinnamic acids as pyruvate carboxylase inhibitors.
(Burkett DJ, Wyatt BN, Mews M, Bautista A, Engel R, Dockendorff C, Donaldson WA, St Maurice M)
Bioorg Med Chem
2019 Sep 15;27(18):4041-4047 PMID: 31351848 SCOPUS ID: 2-s2.0-85070969158 07/29/2019
9 Citations
A high-throughput screening assay for pyruvate carboxylase.
(Wyatt BN, Arnold LA, St Maurice M)
Anal Biochem
2018 Jun 01;550:90-98 PMID: 29655770 SCOPUS ID: 2-s2.0-85046152441 04/16/2018
5 Citations
Allosteric regulation alters carrier domain translocation in pyruvate carboxylase.
(Liu Y, Budelier MM, Stine K, St Maurice M)
Nat Commun
2018 Apr 11;9(1):1384 PMID: 29643369 PMCID: PMC5895798 SCOPUS ID: 2-s2.0-85045259817 04/13/2018
13 Citations
A Paradigm for CH Bond Cleavage: Structural and Functional Aspects of Transition State Stabilization by Mandelate Racemase.
(Bearne SL, St Maurice M)
Adv Protein Chem Struct Biol
2017;109:113-160 PMID: 28683916 SCOPUS ID: 2-s2.0-85020471994 07/08/2017
16 Citations
The urea carboxylase and allophanate hydrolase activities of urea amidolyase are functionally independent.
(Lin Y, Boese CJ, St Maurice M)
Protein Sci
2016 Oct;25(10):1812-24 PMID: 27452902 PMCID: PMC5029531 SCOPUS ID: 2-s2.0-84988377991 07/28/2016
13 Citations
Writing Assignments with a Metacognitive Component Enhance Learning in a Large Introductory Biology Course.
(Mynlieff M, Manogaran AL, St Maurice M, Eddinger TJ)
CBE Life Sci Educ
2014;13(2):311-21 PMID: 26086661 PMCID: PMC4041507 SCOPUS ID: 2-s2.0-84901827772 06/19/2015
37 Citations
Inactivation of Mandelate Racemase by 3-Hydroxypyruvate Reveals a Potential Mechanistic Link between Enzyme Superfamilies.
(Nagar M, Wyatt BN, St Maurice M, Bearne SL)
Biochemistry
2015 May 05;54(17):2747-57 PMID: 25844917 SCOPUS ID: 2-s2.0-84928966672 04/07/2015
8 Citations
The role of biotin and oxamate in the carboxyltransferase reaction of pyruvate carboxylase.
(Lietzan AD, Lin Y, St Maurice M)
Arch Biochem Biophys
2014 Nov 15;562:70-9 PMID: 25157442 PMCID: PMC4197081 SCOPUS ID: 2-s2.0-84907808898 08/27/2014
15 Citations
Functionally diverse biotin-dependent enzymes with oxaloacetate decarboxylase activity.
(Lietzan AD, St Maurice M)
Arch Biochem Biophys
2014 Feb 15;544:75-86 PMID: 24184447 SCOPUS ID: 2-s2.0-84893722694 11/05/2013
19 Citations
Insights into the carboxyltransferase reaction of pyruvate carboxylase from the structures of bound product and intermediate analogs.
(Lietzan AD, St Maurice M)
Biochem Biophys Res Commun
2013 Nov 15;441(2):377-82 PMID: 24157795 PMCID: PMC3894693 SCOPUS ID: 2-s2.0-84887994189 10/26/2013
20 Citations
A substrate-induced biotin binding pocket in the carboxyltransferase domain of pyruvate carboxylase.
(Lietzan AD, St Maurice M)
J Biol Chem
2013 Jul 05;288(27):19915-25 PMID: 23698000 PMCID: PMC3707692 SCOPUS ID: 2-s2.0-84880051370 05/24/2013
24 Citations
The structure of allophanate hydrolase from Granulibacter bethesdensis provides insights into substrate specificity in the amidase signature family.
(Lin Y, St Maurice M)
Biochemistry
2013 Jan 29;52(4):690-700 PMID: 23282241 PMCID: PMC3568674 SCOPUS ID: 2-s2.0-84873880153 01/04/2013
16 Citations
A flagellar A-kinase anchoring protein with two amphipathic helices forms a structural scaffold in the radial spoke complex.
(Sivadas P, Dienes JM, St Maurice M, Meek WD, Yang P)
J Cell Biol
2012 Nov 12;199(4):639-51 PMID: 23148234 PMCID: PMC3494852 SCOPUS ID: 2-s2.0-84871946433 11/14/2012
27 Citations
Structure of mandelate racemase with bound intermediate analogues benzohydroxamate and cupferron.
(Lietzan AD, Nagar M, Pellmann EA, Bourque JR, Bearne SL, St Maurice M)
Biochemistry
2012 Feb 14;51(6):1160-70 PMID: 22264153 PMCID: PMC3313677 SCOPUS ID: 2-s2.0-84856947137 01/24/2012
29 Citations
Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli.
(Lietzan AD, Menefee AL, Zeczycki TN, Kumar S, Attwood PV, Wallace JC, Cleland WW, St Maurice M)
Biochemistry
2011 Nov 15;50(45):9708-23 PMID: 21958016 PMCID: PMC3214759 SCOPUS ID: 2-s2.0-80755174401 10/01/2011
43 Citations
Last update: 10/23/2024