Medical College of Wisconsin
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Sang Kyu Park PhD

Research Scientist I

Institution: Medical College of Wisconsin
Department: Cell Biology, Neurobiology and Anatomy
Program: Developmental and Cell Biology

Publications (11)

  • Target-based discovery of a broad-spectrum flukicide. (Sprague DJ, Park SK, Gramberg S, Bauer L, Rohr CM, Chulkov EG, Smith E, Scampavia L, Spicer TP, Haeberlein S, Marchant JS) Nat Struct Mol Biol 2024 May 07 PMID: 38714890 SCOPUS ID: 2-s2.0-85192232257 05/08/2024    
  • Inflachromene ameliorates Parkinson's disease by targeting Nrf2-binding Keap1. (Yim J, Hwang YS, Lee JJ, Kim JH, Baek JY, Jeong J, Choi YI, Jin BK, Park SB) Chem Sci 2024 Mar 06;15(10):3588-3595 PMID: 38455026 PMCID: PMC10915859 SCOPUS ID: 2-s2.0-85184495313 03/08/2024    
  • The anthelmintic meclonazepam activates a schistosome transient receptor potential channel. (Park SK, Sprague DJ, Rohr CM, Chulkov EG, Petrow I, Kumar S, Marchant JS) J Biol Chem 2024 Jan;300(1):105528 PMID: 38043794 PMCID: PMC10788528 SCOPUS ID: 2-s2.0-85180267343 12/04/2023       1 Citation
  • The Anthelmintic Activity of Praziquantel Analogs Correlates with Structure-Activity Relationships at TRPMPZQ Orthologs. (Sprague DJ, Kaethner M, Park SK, Rohr CM, Harris JL, Maillard D, Spangenberg T, Lundström-Stadelmann B, Marchant JS) ACS Med Chem Lett 2023 Nov 09;14(11):1537-1543 PMID: 37970586 PMCID: PMC10641913 SCOPUS ID: 2-s2.0-85177728490 11/16/2023       2 Citations
  • Metabolism of (R)-Praziquantel versus the Activation of a Parasite Transient Receptor Potential Melastatin Ion Channel. (Friedrich L, Park SK, Ballard P, Ho Baeurle TH, Maillard D, Bödding M, Keiser J, Marchant JS, Spangenberg T) ChemMedChem 2023 Sep 15;18(18):e202300140 PMID: 37272317 PMCID: PMC10530395 SCOPUS ID: 2-s2.0-85161895130 06/05/2023       3 Citations
  • Natural variation in the binding pocket of a parasitic flatworm TRPM channel resolves the basis for praziquantel sensitivity. (Rohr CM, Sprague DJ, Park SK, Malcolm NJ, Marchant JS) Proc Natl Acad Sci U S A 2023 Jan 03;120(1):e2217732120 PMID: 36574686 PMCID: PMC9910428 SCOPUS ID: 2-s2.0-85144783521 12/28/2022       9 Citations
  • Mechanism of praziquantel action at a parasitic flatworm ion channel (Park SK, Friedrich L, Yahya NA, Rohr CM, Chulkov EG, Maillard D, Rippmann F, Spangenberg T, Marchant JS) Science Translational Medicine 22 December 2021;13(625) SCOPUS ID: 2-s2.0-85122014054 12/22/2021       46 Citations
  • Characterization of a new type of neuronal 5-HT G- protein coupled receptor in the cestode nervous system. (Camicia F, Vaca HR, Park SK, Bivona AE, Naidich A, Preza M, Koziol U, Celentano AM, Marchant JS, Rosenzvit MC) PLoS One 2021;16(11):e0259104 PMID: 34762657 PMCID: PMC8584985 SCOPUS ID: 2-s2.0-85118936533 11/12/2021       3 Citations
  • Identification of novel modulators of a schistosome transient receptor potential channel targeted by praziquantel. (Chulkov EG, Smith E, Rohr CM, Yahya NA, Park SK, Scampavia L, Spicer TP, Marchant JS) PLoS Negl Trop Dis 2021 Nov;15(11):e0009898 PMID: 34731172 PMCID: PMC8565742 SCOPUS ID: 2-s2.0-85120649827 11/04/2021       10 Citations
  • The Journey to Discovering a Flatworm Target of Praziquantel: A Long TRP. (Park SK, Marchant JS) Trends Parasitol 2020 Feb;36(2):182-194 PMID: 31787521 PMCID: PMC6937385 SCOPUS ID: 2-s2.0-85075830633 12/04/2019       40 Citations
  • The anthelmintic drug praziquantel activates a schistosome transient receptor potential channel. (Park SK, Gunaratne GS, Chulkov EG, Moehring F, McCusker P, Dosa PI, Chan JD, Stucky CL, Marchant JS) J Biol Chem 2019 Dec 06;294(49):18873-18880 PMID: 31653697 PMCID: PMC6901322 SCOPUS ID: 2-s2.0-85075816525 10/28/2019       67 Citations
    • Last update: 07/09/2024