Medical College of Wisconsin
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Thomas Mcfall PhD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Biochemistry
Program: Program Development

Member of the Cancer Center

Publications (12)

  • Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach. (McFall T, Stites EC) Cell Rep 2021 12 14;37(11):110096 PMID: 34910921 PMCID: PMC8867612 SCOPUS ID: 2-s2.0-85121146579 12/16/2021    
  • KRAS-Mutated, Estrogen Receptor-Positive Low-Grade Serous Ovarian Cancer: Unraveling an Exceptional Response Mystery. (Kato S, McFall T, Takahashi K, Bamel K, Ikeda S, Eskander RN, Plaxe S, Parker B, Stites E, Kurzrock R) Oncologist 2021 04;26(4):e530-e536 PMID: 33528846 PMCID: PMC8018312 SCOPUS ID: 2-s2.0-85101866994 02/03/2021       3 Citations
  • Discernment between candidate mechanisms for KRAS G13D colorectal cancer sensitivity to EGFR inhibitors. (McFall T, Schomburg NK, Rossman KL, Stites EC) Cell Commun Signal 2020 11 05;18(1):179 PMID: 33153459 PMCID: PMC7643456 SCOPUS ID: 2-s2.0-85095115047 11/07/2020       1 Citation
  • A mechanism for the response of KRASG13D expressing colorectal cancers to EGFR inhibitors. (McFall T, Stites EC) Mol Cell Oncol 2020;7(2):1701914 PMID: 32158916 PMCID: PMC7051129 SCOPUS ID: 2-s2.0-85078303987 03/12/2020       3 Citations
  • A systems mechanism for KRAS mutant allele-specific responses to targeted therapy. (McFall T, Diedrich JK, Mengistu M, Littlechild SL, Paskvan KV, Sisk-Hackworth L, Moresco JJ, Shaw AS, Stites EC) Sci Signal 2019 09 24;12(600) PMID: 31551296 PMCID: PMC6864030 SCOPUS ID: 2-s2.0-85072619385 09/26/2019       21 Citations
  • Chronic p27Kip1 Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over-expressing Glucocorticoid Receptor. (Patki M, McFall T, Rosati R, Huang Y, Malysa A, Polin L, Fielder A, Wilson MR, Lonardo F, Back J, Li J, Matherly LH, Bepler G, Ratnam M) Sci Rep 2018 10 30;8(1):16006 PMID: 30375484 PMCID: PMC6207728 SCOPUS ID: 2-s2.0-85055615805 10/31/2018       5 Citations
  • Strategy for Tumor-Selective Disruption of Androgen Receptor Function in the Spectrum of Prostate Cancer. (Rosati R, Polin L, Ducker C, Li J, Bao X, Selvakumar D, Kim S, Xhabija B, Larsen M, McFall T, Huang Y, Kidder BL, Fribley A, Saxton J, Kakuta H, Shaw P, Ratnam M) Clin Cancer Res 2018 12 15;24(24):6509-6522 PMID: 30185422 PMCID: PMC6295231 SCOPUS ID: 2-s2.0-85058440559 09/07/2018       7 Citations
  • Progesterone receptor A promotes invasiveness and metastasis of luminal breast cancer by suppressing regulation of critical microRNAs by estrogen. (McFall T, McKnight B, Rosati R, Kim S, Huang Y, Viola-Villegas N, Ratnam M) J Biol Chem 2018 01 26;293(4):1163-1177 PMID: 29162724 PMCID: PMC5787796 SCOPUS ID: 2-s2.0-85041241242 11/23/2017       23 Citations
  • The Amino-terminal Domain of the Androgen Receptor Co-opts Extracellular Signal-regulated Kinase (ERK) Docking Sites in ELK1 Protein to Induce Sustained Gene Activation That Supports Prostate Cancer Cell Growth. (Rosati R, Patki M, Chari V, Dakshnamurthy S, McFall T, Saxton J, Kidder BL, Shaw PE, Ratnam M) J Biol Chem 2016 Dec 09;291(50):25983-25998 PMID: 27793987 PMCID: PMC5207070 SCOPUS ID: 2-s2.0-85002706288 10/30/2016       9 Citations
  • Hybrid Enzalutamide Derivatives with Histone Deacetylase Inhibitor Activity Decrease Heat Shock Protein 90 and Androgen Receptor Levels and Inhibit Viability in Enzalutamide-Resistant C4-2 Prostate Cancer Cells. (Rosati R, Chen B, Patki M, McFall T, Ou S, Heath E, Ratnam M, Qin Z) Mol Pharmacol 2016 09;90(3):225-37 PMID: 27382012 PMCID: PMC4998664 SCOPUS ID: 2-s2.0-84984848137 07/07/2016       15 Citations
  • Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges. (McFall T, Patki M, Rosati R, Ratnam M) Oncotarget 2015 Oct 20;6(32):33146-64 PMID: 26356672 PMCID: PMC4741755 SCOPUS ID: 2-s2.0-84946031365 09/12/2015       10 Citations
  • Glucocorticoid receptor status is a principal determinant of variability in the sensitivity of non-small-cell lung cancer cells to pemetrexed. (Patki M, Gadgeel S, Huang Y, McFall T, Shields AF, Matherly LH, Bepler G, Ratnam M) J Thorac Oncol 2014 Apr;9(4):519-26 PMID: 24736075 PMCID: PMC4075060 SCOPUS ID: 2-s2.0-84922479677 04/17/2014       21 Citations
  • Last update: 12/23/2021