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Yan-Qing Ma PhD
Associate Investigator
Institution:
BloodCenter of Wisconsin
Department:
Blood Research Institute
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Publications (9)
Integrin αIIbβ3
(Bledzka K, Pesho M and Ma Y.-Q. and Plow EF)
Platelets 3/e
Chapter 8, Michelson 2013 05/22/2014
Kindlin-2 regulates hemostasis by controlling endothelial cell-surface expression of ADP/AMP catabolic enzymes via a clathrin-dependent mechanism.
(Pluskota E, Ma Y, Bledzka KM, Bialkowska K, Soloviev DA, Szpak D, Podrez EA, Fox PL, Hazen SL, Dowling JJ, Ma YQ, Plow EF)
Blood
2013 Oct 03;122(14):2491-9 PMID: 23896409 PMCID: PMC3790514 SCOPUS ID: 2-s2.0-84887629722 07/31/2013
35 Citations
Integrity of kindlin-2 FERM subdomains is required for supporting integrin activation.
(Xu Z, Gao J, Hong J, Ma YQ)
Biochem Biophys Res Commun
2013 May 03;434(2):382-7 PMID: 23578664 SCOPUS ID: 2-s2.0-84877061239 04/13/2013
17 Citations
Spatial coordination of kindlin-2 with talin head domain in interaction with integrin β cytoplasmic tails.
(Bledzka K, Liu J, Xu Z, Perera HD, Yadav SP, Bialkowska K, Qin J, Ma YQ, Plow EF)
J Biol Chem
2012 Jul 13;287(29):24585-94 PMID: 22648415 PMCID: PMC3397883 SCOPUS ID: 2-s2.0-84863793892 06/01/2012
69 Citations
Membrane binding of the N-terminal ubiquitin-like domain of kindlin-2 is crucial for its regulation of integrin activation.
(Perera HD, Ma YQ, Yang J, Hirbawi J, Plow EF, Qin J)
Structure
2011 Nov 09;19(11):1664-71 PMID: 22078565 PMCID: PMC3217186 SCOPUS ID: 2-s2.0-80855133531 11/15/2011
47 Citations
Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation.
(Liu J, Fukuda K, Xu Z, Ma YQ, Hirbawi J, Mao X, Wu C, Plow EF, Qin J)
J Biol Chem
2011 Dec 16;286(50):43334-42 PMID: 22030399 PMCID: PMC3234820 SCOPUS ID: 2-s2.0-83355174039 10/28/2011
85 Citations
The integrin coactivator kindlin-2 plays a critical role in angiogenesis in mice and zebrafish.
(Pluskota E, Dowling JJ, Gordon N, Golden JA, Szpak D, West XZ, Nestor C, Ma YQ, Bialkowska K, Byzova T, Plow EF)
Blood
2011 May 05;117(18):4978-87 PMID: 21378273 PMCID: PMC3100704 SCOPUS ID: 2-s2.0-79955980408 03/08/2011
68 Citations
Tyrosine phosphorylation of integrin beta3 regulates kindlin-2 binding and integrin activation.
(Bledzka K, Bialkowska K, Nie H, Qin J, Byzova T, Wu C, Plow EF, Ma YQ)
J Biol Chem
2010 Oct 01;285(40):30370-4 PMID: 20702409 PMCID: PMC2945529 SCOPUS ID: 2-s2.0-77957269801 08/13/2010
45 Citations
The integrin co-activator Kindlin-3 is expressed and functional in a non-hematopoietic cell, the endothelial cell.
(Bialkowska K, Ma YQ, Bledzka K, Sossey-Alaoui K, Izem L, Zhang X, Malinin N, Qin J, Byzova T, Plow EF)
J Biol Chem
2010 Jun 11;285(24):18640-9 PMID: 20378539 PMCID: PMC2881789 SCOPUS ID: 2-s2.0-77953317401 04/10/2010
84 Citations
Last update: 04/01/2013