Lymphatic malformation: predictive factors for recurrence. Otolaryngol Head Neck Surg 2000 Dec;123(6):706-10
Date
12/12/2000Pubmed ID
11112962DOI
10.1067/mhn.2000.110963Scopus ID
2-s2.0-0033674173 (requires institutional sign-in at Scopus site) 64 CitationsAbstract
OBJECTIVE: Although lymphatic malformations are often found to be well circumscribed when surgery is undertaken in early childhood, complete surgical excision can be difficult when the lesion is infiltrative. This study retrospectively evaluates these patients in an attempt to identify prognostic factors that may predict recurrence.
STUDY DESIGN AND SETTING: A retrospective chart review was conducted covering the years 1991 to 1998. Seventeen patients were identified having undergone 32 surgical resections of tumors described as lymphatic malformations. Data abstracted from the charts included the site of the lesion, surgical and histologic assessment of encapsulation, and status at follow-up examination.
RESULTS: Six of 17 patients developed a recurrence after surgery. Correlation between recurrence and histologic or operative impressions of encapsulation was significant by chi(2) analysis (P<0.01).
CONCLUSION: On the basis of the findings of this case series, lymphatic malformations that are found to be nonencapsulated and infiltrative by intraoperative or histologic assessment are more likely to recur.
Author List
Fliegelman LJ, Friedland D, Brandwein M, Rothschild MMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Chi-Square Distribution
Child
Child, Preschool
Female
Head and Neck Neoplasms
Humans
Infant
Lymphangioma
Male
Middle Aged
Neoplasm Recurrence, Local
Predictive Value of Tests
Prognosis
Reoperation
Retrospective Studies
Risk Factors
Single-Blind Method
