Neonatal diuretic therapy: furosemide, thiazides, and spironolactone. Clin Perinatol 2012 Mar;39(1):209-20
Date
02/22/2012Pubmed ID
22341547DOI
10.1016/j.clp.2011.12.007Scopus ID
2-s2.0-84857085333 (requires institutional sign-in at Scopus site) 48 CitationsAbstract
Diuretics are commonly used to treat infants with oxygen-dependent chronic lung disease. However, there are limited data suggesting a beneficial effect of long-term diuretic therapy on pulmonary function or clinical outcome in this population. Furthermore, data available for review were primarily obtained before the widespread use of antenatal steroids or surfactant replacement therapy, before recognition of the new bronchopulmonary dysplasia. If used in this population, limitations of diuretic therapy as well as significant side effects need to be understood and a rationale approach to clinical use developed on a patient-centered basis.
Author List
Segar JLAuthor
Jeffrey L. Segar MD Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Bronchopulmonary DysplasiaDiuretics
Ductus Arteriosus, Patent
Furosemide
Humans
Infant, Newborn
Infant, Newborn, Diseases
Infant, Premature
Infant, Premature, Diseases
Kidney
Kidney Function Tests
Lung Diseases
Respiratory Function Tests
Spironolactone
Thiazides
