Strategies to prevent bacterial and fungal infection in the neonatal intensive care unit. Clin Perinatol 2009 Mar;36(1):1-13
Date
01/24/2009Pubmed ID
19161861DOI
10.1016/j.clp.2008.09.005Scopus ID
2-s2.0-58249087610 (requires institutional sign-in at Scopus site) 32 CitationsAbstract
Hospital-acquired infections are one of the leading causes of preventable morbidity and mortality in neonatal intensive care units (NICUs). Device-related infections, such as catheter-associated blood stream infections (CABSIs) and ventilator-associated pneumonia (VAP), are the most common nosocomial infections. This review examines the pathogenesis of CABSIs and methods, widely accepted and novel, that can be used to help prevent them. Strategies to prevent fungal infections, which are often associated with the presence of a central venous catheter, are also reviewed. Finally, the dilemmas in the diagnosis and prevention of VAP in the NICU are discussed.
Author List
Garland JS, Uhing MRMESH terms used to index this publication - Major topics in bold
Bacterial InfectionsCatheterization
Catheters, Indwelling
Cross Infection
Humans
Infant, Newborn
Intensive Care Units, Neonatal
Mycoses
Pneumonia, Ventilator-Associated
