Medical College of Wisconsin
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Continuous quantitative local cerebral blood flow measurement. Calibration of thermal conductivity measurements by the hydrogen clearance method. Stroke 1980;11(6):661-4

Date

11/01/1980

Pubmed ID

6451956

DOI

10.1161/01.str.11.6.661

Scopus ID

2-s2.0-0019132426 (requires institutional sign-in at Scopus site)   15 Citations

Abstract

The capability of a miniaturized probe to measure local cerebral blood flow in a continuous and quantitative manner is described. The incorporation of thermal conductivity measurements using the isothermal principle with the hydrogen clearance method allows calibration of the thermal conductivity component in absolute terms. Evaluation of this system in 14 cats showed a linear relationship between both measurement methods. The major limitation of this combination probe system is the need for routine intermittent recalibration in order that changes of tissues thermal conductivity induced by physiologic alterations during the experimental procedure may be recognized and resolved.

Author List

Cusick JF, Myklebust J

Author

Joseph F. Cusick MD Adjunct Professor in the Neurosurgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Brain
Calibration
Cats
Cerebrovascular Circulation
Hot Temperature
Hydrogen
Plethysmography, Impedance
Rheology
Thermal Conductivity
Thermometers