Aggressive combined modality therapy for recurrent colorectal cancer involving the duodenum and pancreas: a report of 5 cases. Clin Colorectal Cancer 2008 Sep;7(5):338-42
Date
09/17/2008Pubmed ID
18794067DOI
10.3816/CCC.2008.n.045Scopus ID
2-s2.0-53849122293 (requires institutional sign-in at Scopus site)Abstract
We report 5 cases in which the recurrence of colorectal cancer (CRC) presented as a mass involving the duodenum and pancreas. The treatment approach for such recurrences is not standardized, and in particular, the benefits of pancreaticoduodenectomy for such cases are not known. We describe the successful use of aggressive multimodality treatment with chemotherapy, radiation, and en bloc surgical resection. Such trimodality therapy can result in durable palliation of symptoms and long-term survival for patients with recurrent CRC involving the duodenum and pancreas, even when other metastases are present.
Author List
Overman MJ, Fogelman D, Al-Kali A, Crane CH, Evans D, Abdalla EK, Pisters P, Kopetz S, Eng C, Wolff RAAuthor
Douglas B. Evans MD Chair, Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdenocarcinomaAged
Colorectal Neoplasms
Combined Modality Therapy
Disease-Free Survival
Duodenal Neoplasms
Humans
Male
Middle Aged
Neoplasm Recurrence, Local
Pancreatic Neoplasms
Retreatment
