Bone marrow transplant nephropathy: radiation nephritis revisited. Nephron 1995;70(2):217-22
Date
01/01/1995Pubmed ID
7566307DOI
10.1159/000188587Scopus ID
2-s2.0-0029059253 (requires institutional sign-in at Scopus site) 91 CitationsAbstract
Late-onset renal failure occurs in up to 20% of survivors of bone marrow transplantation. Total body irradiation is a major factor in this syndrome, so-called bone marrow transplant nephropathy (BMT NP), which is defined by disproportionate anemia, hypertension, and azotemia. Previous or concurrent chemotherapy may potentiate the effect of radiation on the kidney. Kidney function may decline acutely or more gradually, with eventual long-term stabilization. Patient survival is associated with control of the blood pressure. BMT NP is a recognized complication of bone marrow transplantation, which will require ongoing attention.
Author List
Cohen EP, Lawton CA, Moulder JEMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Bone Marrow Transplantation
Child
Hematologic Diseases
Humans
Hypertension
Kidney
Kidney Failure, Chronic
Plasmapheresis
Survival Analysis
Survivors
Time Factors
