Medical College of Wisconsin
CTSIResearch InformaticsREDCap

The Gene Ontology in 2010: extensions and refinements. Nucleic Acids Res 2010 Jan;38(Database issue):D331-5

Date

11/19/2009

Pubmed ID

19920128

Pubmed Central ID

PMC2808930

DOI

10.1093/nar/gkp1018

Scopus ID

2-s2.0-75849158230 (requires institutional sign-in at Scopus site)   409 Citations

Abstract

The Gene Ontology (GO) Consortium (http://www.geneontology.org) (GOC) continues to develop, maintain and use a set of structured, controlled vocabularies for the annotation of genes, gene products and sequences. The GO ontologies are expanding both in content and in structure. Several new relationship types have been introduced and used, along with existing relationships, to create links between and within the GO domains. These improve the representation of biology, facilitate querying, and allow GO developers to systematically check for and correct inconsistencies within the GO. Gene product annotation using GO continues to increase both in the number of total annotations and in species coverage. GO tools, such as OBO-Edit, an ontology-editing tool, and AmiGO, the GOC ontology browser, have seen major improvements in functionality, speed and ease of use.

Author List

Gene Ontology Consortium

Author

Stanley J. Laulederkind Research Scientist II in the Physiology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Computational Biology
Databases, Genetic
Databases, Nucleic Acid
Databases, Protein
Genomics
Humans
Information Storage and Retrieval
Internet
Software
User-Computer Interface
Vocabulary, Controlled