Auditory evoked brainstem and middle latency responses in Macaca mulatta and humans. Hear Res 1995 Sep;89(1-2):212-25
Date
09/01/1995Pubmed ID
8600129DOI
10.1016/0378-5955(95)00140-7Scopus ID
2-s2.0-0028841091 (requires institutional sign-in at Scopus site) 24 CitationsAbstract
Early (ABRs) and middle (MLRs) surface-recorded auditory evoked potentials were compared in eight adult monkeys (Macaca mulatta) and eight adult humans. Responses whose probable generators were the cochlear nucleus and lateral lemniscus were of shorter latency and larger amplitude in monkeys. Relative to humans, ABR response latencies in monkeys were less affected by stimulus intensity, stimulus rate, and masker level. In contrast, monkey amplitudes were relatively more affected by those same stimulus parameters. The most prominent MLR wave was longer in latency and greater in amplitude in humans than the homologous wave in monkeys. The reduction in amplitude of that wave with increasing rate was greater for humans than monkeys. Temporal interactions (the effect of prior stimuli on the response to current stimulation) were investigated from a non-linear systems identification framework using maximum length sequences (MLSs). Both monkey and human auditory systems were second and probably third-order systems at the levels assessed. As the separations between the stimulus pulses decreased, evidence for temporal interactions became more prominent, reached a maximum, and then decreased with further decreases in stimulus pulse separation. At the highest stimulus rates presented, variations in temporal spacing among stimuli had less of an effect on monkey than human evoked responses.
Author List
Lasky RE, Maier MM, Snodgrass EB, Laughlin NK, Hecox KEMESH terms used to index this publication - Major topics in bold
Acoustic StimulationAdult
Animals
Evoked Potentials, Auditory
Evoked Potentials, Auditory, Brain Stem
Female
Humans
Macaca mulatta
Male
Perceptual Masking
Psychoacoustics
Species Specificity
