Qualitative effect on mRNAs of injury-associated proteins by cell phone like radiation in rat facial nerves. Electromagn Biol Med 2009;28(4):383-90
Date
12/19/2009Pubmed ID
20017629DOI
10.3109/15368370903287614Scopus ID
2-s2.0-73349101060 (requires institutional sign-in at Scopus site) 13 CitationsAbstract
Rats were exposed to cell phone radiation for 6 hours per day for 18 weeks. The buccal and mandibular branches of the facial nerve were evaluated for this study. The mRNA levels of four proteins that are usually up regulated when an injury has occurred were investigated; included were Calcium ATP-ase, Endothelin, Neural Cell Adhesion Molecule, and Neural Growth Factor. These isolated mRNAs were subjected to RT-PCR and all four were up regulated. The mandibular nerve showed a higher and broader level of up regulation than the buccal nerve. All four mRNA up regulations for the mandibular nerve and two for the buccal nerve were also statistically significant. These specific injury-related findings were mild. As the use of these cell phones continues, there most likely will be permanent damage to these tissues over the years and the likelihood of tumors, cancers, and system failures will potentially increase.
Author List
Yan JG, Agresti M, Zhang LL, Yan Y, Matloub HSMESH terms used to index this publication - Major topics in bold
AnimalsCalcium-Transporting ATPases
Cell Phone
Dose-Response Relationship, Radiation
Endothelins
Facial Nerve
Facial Nerve Injuries
Gene Expression Regulation
Male
Mandibular Nerve
Nerve Growth Factors
Nerve Tissue Proteins
Neural Cell Adhesion Molecules
RNA, Messenger
Radio Waves
Rats
Rats, Sprague-Dawley
Reverse Transcriptase Polymerase Chain Reaction
Time Factors
Trigeminal Nerve Injuries
