Faculty Collaboration Database

Hepatic helical CT: contrast material injection protocol. Radiology 1994 Aug;192(2):367-71

Date

08/01/1994

Pubmed ID

8029399

DOI

10.1148/radiology.192.2.8029399

Scopus ID

2-s2.0-0028100912 (requires institutional sign-in at Scopus site)   103 Citations

Abstract

PURPOSE: To develop and compare contrast material injection protocols suitable for hepatic helical computed tomography (CT).

MATERIALS AND METHODS: Monophasic and biphasic helical CT were performed with contrast material with an iodine load of 50 g at 3 mL/sec for 60 seconds or at 5 mL/sec for 10 seconds and 2 mL/sec for 65 seconds, respectively. In 58 men and 51 women, aged 22-77 years, aortic and hepatic enhancement curves were constructed from a cluster acquisition with a slip-ring scanner operating in a nonhelical mode.

RESULTS: The monophasic protocol produced a higher peak aortic enhancement (180 HU +/- 47 [+/- 1 standard deviation]) than the biphasic protocol (150 HU +/- 24). Peak hepatic enhancement (63-64 HU +/- 15) was equivalent. Calculated equilibrium time for the monophasic protocol was 95.1 seconds and for the biphasic protocol was 101.4 seconds. The contrast enhancement index differed only marginally between the two protocols (P < .4).

CONCLUSION: Monophasic and biphasic protocols produced equivalent results when tailored for the shorter temporal window of a rapid-sequence helical acquisition.

Author List

Foley WD, Hoffmann RG, Quiroz FA, Kahn CE Jr, Perret RS

Authors

William Dennis Foley MBBS Emeritus Professor in the Radiology department at Medical College of Wisconsin
Francisco Quiroz MD Emeritus Professor in the Radiology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Aged
Aortography
Contrast Media
Female
Humans
Injections, Intravenous
Liver
Male
Middle Aged
Tomography, X-Ray Computed