Medical College of Wisconsin
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[Cell strains of A431 epidermoid carcinoma with altered epidermal growth factor reception]. Tsitologiia 1989 Mar;31(3):319-23

Date

03/01/1989

Pubmed ID

2787558

Scopus ID

2-s2.0-0024524208 (requires institutional sign-in at Scopus site)   1 Citation

Abstract

Epidermal growth factor inhibits proliferation of A431 cells when added to the cultural medium. Strains of A431 cells, resistant to EGF (800 ng/ml), were obtained by one-step selection after the treatment of these cells by 1-methyl-3-nitro-1-nitrosoguanidine (MNNG). Two of the obtained strains differ from the initial line in the EGF reception.

Author List

Gudkova DA, Sorokin AB

Author

Andrey Sorokin PhD Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Carcinoma, Squamous Cell
Cell Division
Cell Line
Depression, Chemical
Dose-Response Relationship, Drug
Drug Resistance
Epidermal Growth Factor
ErbB Receptors
Humans
Iodine Radioisotopes
Methylnitronitrosoguanidine
Tumor Cells, Cultured