Faculty Collaboration Database

Enterogastric bile reflux during technetium-99m-sestamibi cardiac imaging. J Nucl Med 1996 Aug;37(8):1285-8

Date

08/01/1996

Pubmed ID

8708757

Scopus ID

2-s2.0-0029764839 (requires institutional sign-in at Scopus site)   17 Citations

Abstract

UNLABELLED: Enterogastric bile reflux (EGBR), a risk factor for both gastritis and esophagitis, is a potentially treatable noncoronary cause for chest pain.

METHODS: To investigate the frequency of EGBR during different 99mTc-sestamibi cardiac imaging, 1405 consecutive 99mTc-sestamibi SPECT myocardial perfusion studies were reviewed.

RESULTS: One hundred sixteen of the 1405 patient studies (8.3%) showed EGBR with roughly equal numbers of patients having marked (43 patients), moderate (38 patients) or minimal (35 patients) intensity of abnormal gastric activity. Two examinations showed gastroesophageal reflux of activity. EGBR was less frequent with treadmill stress testing (5.5% patients) than with pharmacologic stress testing using either dipyridamole (11% of patients) or dobutamine (9.2% of patients) (p > 0.005). EGBR also was more frequent in patients over 40 yr of age. Finally, the prevalence of upper gastrointestinal symptoms and the frequency of established upper gastrointestinal diagnoses correlated strongly with the presence and intensity of EGBR.

CONCLUSION: Clarification of the full clinical significance of EGBR during 99mTc-sestamibi cardiac imaging is a topic for future research. Nonetheless, the imaging finding of EGBR may, in fact, identify a potentially treatable noncoronary cause for chest pain.

Author List

Kabasakal L, Collier BD, Shaker R, Hellman RS, Smart S, Ozker K, Krasnow AZ, Isitman AT

Author

Reza Shaker MD Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Bile Reflux
Case-Control Studies
Chest Pain
Coronary Disease
Dipyridamole
Exercise Test
Female
Heart
Humans
Male
Middle Aged
Prevalence
Retrospective Studies
Technetium Tc 99m Sestamibi
Tomography, Emission-Computed, Single-Photon
Vasodilator Agents