Bilateral retinal embolization associated with intralesional corticosteroid injection for capillary hemangioma of infancy. J Pediatr Ophthalmol Strabismus 1993;30(1):4-7
Date
01/01/1993Pubmed ID
8455125DOI
10.3928/0191-3913-19930101-03Scopus ID
2-s2.0-0027533788 (requires institutional sign-in at Scopus site) 89 CitationsAbstract
A 2-month-old female infant underwent intralesional corticosteroid injection for a capillary hemangioma that was causing amblyopia of the right eye from ptosis, globe displacement, and astigmatism. Forty-eight hours after the injection, the infant's parents noted that she was visually inattentive. On examination, she could not fixate or follow with either eye, and an afferent pupillary defect was present in the left eye. Ophthalmoscopy showed scattered areas of intraretinal hemorrhage in the right eye and extensive preretinal and intraretinal hemorrhages in the left eye. Ten months after injection, the hemangioma had greatly regressed, and visual acuity in the right eye was felt to be normal. The left eye had unsteady fixation with a persistent afferent pupillary defect and macular scarring. Retrograde flow of the corticosteroid suspension through the hemangioma's feeder vessels, probably originating from both ophthalmic arteries, is the most likely explanation for this complication.
Author List
Ruttum MS, Abrams GW, Harris GJ, Ellis MKAuthor
Gerald J. Harris MD Professor in the Ophthalmology and Visual Sciences department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
BetamethasoneEmbolism
Eyelid Neoplasms
Female
Hemangioma
Humans
Infant
Injections, Intralesional
Radiography
Retinal Diseases
Retinal Hemorrhage
Triamcinolone