Lipid hydroperoxide analysis by high-performance liquid chromatography with mercury cathode electrochemical detection. Methods Enzymol 1999;300:23-33
Date
01/27/1999Pubmed ID
9919505DOI
10.1016/s0076-6879(99)00109-3Scopus ID
2-s2.0-0031769439 (requires institutional sign-in at Scopus site) 52 CitationsAbstract
In addition to the applications described, HPLC-EC(Hg) can be used for determining LOOHs in lipoproteins and for monitoring LOOH detoxification in cells. As it continues to be developed and refined, this approach should prove to be valuable not only for ultrasensitive determination of lipid-derived peroxides, but protein- and nucleic acid-derived peroxided as well.
Author List
Korytowski W, Geiger PG, Girotti AWAuthor
Albert W. Girotti PhD Adjunct Professor in the Biochemistry department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsChromatography, High Pressure Liquid
Electrochemistry
Electrodes
Glutathione Peroxidase
Leukemia L1210
Lipid Peroxides
Mercury
Oxidation-Reduction
Oxidative Stress