Factors in the technical quality of gadolinium enhanced magnetic resonance angiography for pulmonary embolism in PIOPED III. Int J Cardiovasc Imaging 2012 Feb;28(2):303-12
Date
02/25/2011Pubmed ID
21347594Pubmed Central ID
PMC3196681DOI
10.1007/s10554-011-9820-7Scopus ID
2-s2.0-84861481124 (requires institutional sign-in at Scopus site) 25 CitationsAbstract
In a multi-center trial, gadolinium enhanced magnetic resonance angiography (MRA) for diagnosis of acute pulmonary embolism (PE) had a high rate of technically inadequate images. Accordingly, we evaluated the reasons for poor quality MRA of the pulmonary arteries in these patients. We performed a retrospective analysis of the data collected in the PIOPED III study. We assessed the relationship to the proportion of examinations deemed "uninterpretable" by central readers to the clinical centers, MR equipment platform and vendors, degree of vascular opacification in different orders of pulmonary arteries; type, frequency and severity of image artifacts; patient co-morbidities, symptoms and signs; and reader characteristics. Centers, MR equipment vendor and platform, degree of vascular opacification, and motion artifacts influenced the likelihood of central reader determinations that images were "uninterpretable". Neither the reader nor patient characteristics (age, body mass index, respiratory rate, heart rate) correlated with the likelihood of determining examinations "uninterpretable". Vascular opacification and motion artifact are the principal factors influencing MRA interpretability. Some centers obtain better images more consistently, but the reasons for differences between centers are unclear.
Author List
Sostman HD, Jablonski KA, Woodard PK, Stein PD, Naidich DP, Chenevert TL, Weg JG, Hales CA, Hull RD, Goodman LR, Tapson VFMESH terms used to index this publication - Major topics in bold
Acute DiseaseArtifacts
Chi-Square Distribution
Clinical Trials as Topic
Contrast Media
Female
Gadolinium DTPA
Humans
Logistic Models
Magnetic Resonance Angiography
Male
Meglumine
Multicenter Studies as Topic
Multivariate Analysis
Observer Variation
Odds Ratio
Organometallic Compounds
Predictive Value of Tests
Pulmonary Artery
Pulmonary Embolism
Reproducibility of Results
Retrospective Studies
United States
