Paraneoplastic cicatricial pemphigoid. Br J Dermatol 1999 Jul;141(1):127-31
Date
07/27/1999Pubmed ID
10417528DOI
10.1046/j.1365-2133.1999.02933.xScopus ID
2-s2.0-0032864629 (requires institutional sign-in at Scopus site) 45 CitationsAbstract
We report a 39-year-old woman with antiepiligrin cicatricial pemphigoid (CP) in association with non-small cell carcinoma of the lung. At presentation, mucosal lesions showed minimal response to combined systemic immunosuppressive agents. Following the diagnosis of non-small cell lung carcinoma and subsequent treatment with gemcitabine (a second-line chemotherapeutic agent), a significant reduction in both tumour mass and mucosal blistering was observed. Metastatic disease was subsequently associated with recurrent oral erosions. We believe this patient represents the first reported case of paraneoplastic CP.
Author List
Setterfield J, Shirlaw PJ, Lazarova Z, Bryant BM, Bhogal BS, Harman K, Challacombe SJ, Black MMMESH terms used to index this publication - Major topics in bold
AdultCarcinoma, Non-Small-Cell Lung
Cell Adhesion Molecules
Complement C3
Female
Fluorescent Antibody Technique, Direct
Humans
Immunoglobulin G
Lung Neoplasms
Microscopy, Immunoelectron
Paraneoplastic Syndromes
Pemphigoid, Benign Mucous Membrane
Skin
