Mapping of semantic, phonological, and orthographic verbal working memory in normal adults with functional magnetic resonance imaging. Neuropsychology 1999 Apr;13(2):171-87
Date
06/03/1999Pubmed ID
10353369DOI
10.1037//0894-4105.13.2.171Scopus ID
2-s2.0-0032894377 (requires institutional sign-in at Scopus site) 95 CitationsAbstract
Twelve neurologically normal participants (4 men and 8 women) performed semantic, phonological, and orthographic working memory tasks and a control task during functional magnetic resonance imaging. Divergent regions of the posterior left hemisphere used for decoding and storage of information emerged in each working memory versus control task comparison. These regions were consistent with previous literature on processing mechanisms for semantic, phonological, and orthographic information. Further, working memory versus control task differences extended into the left frontal lobe, including premotor cortex, and even into subcortical structures. Findings were consistent with R. C. Martin and C. Romani's (1994) contention that different forms of verbal working memory exist and further suggest that a reconceptualization of premotor cortex functions is needed.
Author List
Crosson B, Rao SM, Woodley SJ, Rosen AC, Bobholz JA, Mayer A, Cunningham JM, Hammeke TA, Fuller SA, Binder JR, Cox RW, Stein EAAuthor
Jeffrey R. Binder MD Professor in the Neurology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Brain Mapping
Dominance, Cerebral
Female
Frontal Lobe
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Male
Memory, Short-Term
Prefrontal Cortex
Psycholinguistics
Psychomotor Performance
Reference Values
Verbal Learning
Word Association Tests
