Medical College of Wisconsin
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MR imaging of optic nerve lesions: value of gadopentetate dimeglumine and fat-suppression technique. AJNR Am J Neuroradiol 1990;11(4):749-54

Date

07/01/1990

Pubmed ID

2114763

Pubmed Central ID

PMC8331640

Scopus ID

2-s2.0-0025108648 (requires institutional sign-in at Scopus site)   47 Citations

Abstract

Eleven patients with known or suspected optic nerve lesions and eight normal subjects were examined with spin-echo technique at 1.5 T with unenhanced T1-weighted imaging, IV gadopentetate-dimeglumine-enhanced T1-weighted imaging, and enhanced T1-weighted imaging with fat suppression. Two pathologically proved and four presumed optic nerve meningiomas demonstrated significant enhancement and were best seen with the fat-suppression technique. None of the three presumed optic nerve gliomas nor the optic nerves of normal subjects demonstrated qualitative enhancement. We conclude that the use of a fat-suppression technique with gadopentetate dimeglumine enhancement improves delineation of enhancing optic nerve lesions. This technique should be useful for evaluating other anatomic regions where enhancing tissue marginates fat.

Author List

Hendrix LE, Kneeland JB, Haughton VM, Daniels DL, Szumowski J, Williams AL, Mark LP, Czervionke LF



MESH terms used to index this publication - Major topics in bold

Adult
Aged
Contrast Media
Drug Combinations
Gadolinium
Gadolinium DTPA
Glioma
Humans
Magnetic Resonance Imaging
Meglumine
Meningeal Neoplasms
Meningioma
Middle Aged
Optic Nerve Diseases
Organometallic Compounds
Pentetic Acid
Sorbitol