An analysis of thirty cases of orbital lymphangioma. Pathophysiologic considerations and management recommendations. Ophthalmology 1990 Dec;97(12):1583-92
Date
12/01/1990Pubmed ID
2087290DOI
10.1016/s0161-6420(90)32370-9Scopus ID
2-s2.0-0025604783 (requires institutional sign-in at Scopus site) 119 CitationsAbstract
Thirty cases of orbital lymphangioma were reviewed. Clinical, imaging, and microscopic findings were integrated to develop a pathophysiologic construct and management guidelines. The basic lesion might be considered an abortive vascular system which arborizes among normal structures. Intrinsic hemorrhage expands portions of the small-caliber network into large blood cysts, prompting clinical recognition. While major hemorrhage led to early surgery in 12 cases, long pretreatment intervals could be analyzed in 17 others. Twelve patients had second hemorrhages of varied magnitude, from 2 weeks to 15 years after initial recognition; five patients did not in an average of 6.8 years. Some blood cysts contracted spontaneously. Among 23 operated cases, 12 patients had major new bleeds from 4 days to 12 years after initial surgery; 11 patients did not in an average of 4.2 years. Poor final visual acuity was associated with multiple surgeries. The authors advocate conservatism in surgical case selection and in operative dissection.
Author List
Harris GJ, Sakol PJ, Bonavolontà G, De Conciliis CAuthor
Gerald J. Harris MD Professor in the Ophthalmology and Visual Sciences department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Aged
Child
Child, Preschool
Female
Hemorrhage
Humans
Infant
Infant, Newborn
Lymphangioma
Magnetic Resonance Imaging
Male
Orbital Neoplasms
Reoperation
Tomography, X-Ray Computed
Ultrasonography
Visual Acuity