Faculty Collaboration Database

Skin breakdown in children and high-frequency oscillatory ventilation. Arch Phys Med Rehabil 1998 Dec;79(12):1565-9

Date

12/23/1998

Pubmed ID

9862302

DOI

10.1016/s0003-9993(98)90422-1

Scopus ID

2-s2.0-0031674008 (requires institutional sign-in at Scopus site)   13 Citations

Abstract

OBJECTIVE: To investigate the relationship of high-frequency oscillatory ventilation (HFOV) to skin breakdown on the scalp and ears in mechanically ventilated children.

STUDY DESIGN: Retrospective cohort study of 32 patients supported with HFOV paired with 32 patients supported with conventional mechanical ventilation (CV) in a pediatric intensive care unit (PICU).

RESULTS: By univariate analysis, more HFOV patients had skin breakdown than did the CV patients (53% vs 12.5%, p=.001); HFOV patients also had greater severity of illness (Pediatric Risk of Mortality scores), higher mortality, and longer durations of neuromuscular blockade, low systolic blood pressure, and time exposed to risk. Life table analysis demonstrated no difference in the rate of skin breakdown between HFOV and CV patients. Multifactorial analysis showed that only PICU time at risk was a risk factor for skin breakdown.

CONCLUSIONS: HFOV was not an independent risk factor for the development of skin breakdown. PICU time at risk was the sole risk factor for the development of skin breakdown in all mechanically ventilated patients in the PICU.

Author List

Schmidt JE, Berens RJ, Zollo MB, Weisner M, Weigle CG

Author

Richard J. Berens MD Professor in the Anesthesiology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Analysis of Variance
Child, Preschool
Ear
Female
High-Frequency Ventilation
Humans
Incidence
Infant
Life Tables
Male
Proportional Hazards Models
Respiration, Artificial
Retrospective Studies
Risk Factors
Scalp
Skin Ulcer
Survival Analysis
Time Factors