Faculty Collaboration Database

High-resolution in vivo diffusion tensor imaging of the injured cat spinal cord using self-navigated, interleaved, variable-density spiral acquisition (SNAILS-DTI). Magn Reson Imaging 2010 Nov;28(9):1353-60

Date

08/28/2010

Pubmed ID

20797830

DOI

10.1016/j.mri.2010.06.006

Scopus ID

2-s2.0-77958159554 (requires institutional sign-in at Scopus site)   15 Citations

Abstract

Diffusion tensor magnetic resonance imaging (DTI) is useful for studying the microstructural changes in the spinal cord following traumatic injury; however, image quality is generally poor due to the small size of the spinal cord, physiological motion and susceptibility artifacts. Self-navigated, interleaved, variable-density spiral diffusion tensor imaging (SNAILS-DTI) is a distinctive pulse sequence that bypasses many of the challenges associated with DTI of the spinal cord, particularly if imaging gradient hardware is of conventional quality. In the current study, we have demonstrated the feasibility of implementing SNAILS-DTI on a clinical 3.0-T MR scanner and examined the effect of navigator filter parameters on image quality and reconstruction time. Results demonstrate high-quality, high-resolution (546 μm×546 μm) in vivo DTI images of the cat spinal cord after traumatic spinal cord injury.

Author List

Ellingson BM, Sulaiman O, Kurpad SN

Author

Shekar N. Kurpad MD, PhD Sr Associate Dean, Professor in the Neurosurgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Algorithms
Animals
Cats
Diagnostic Imaging
Diffusion Magnetic Resonance Imaging
Diffusion Tensor Imaging
Female
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Normal Distribution
Pilot Projects
Spinal Cord
Spinal Cord Injuries