Faculty Collaboration Database

In vivo MRI electrical impedance tomography (MREIT) of tumors. Technol Cancer Res Treat 2006 Aug;5(4):381-7

Date

07/27/2006

Pubmed ID

16866568

Scopus ID

2-s2.0-33748036068 (requires institutional sign-in at Scopus site)   44 Citations

Abstract

A significant increase in electrical conductivity of neoplasticities compared to healthy tissues and benign formations has been reported in several studies. We previously reported preliminary results with MR based Electrical Impedance Tomography (MREIT) on several phantoms and a single animal. In the presented study, we applied the technique on ten tumor-bearing rats and collected MREIT images to investigate the potential of MREIT for characterizing malignant tumors. Results show that the tumors had significantly higher mean conductivity compared to the mean of conductivity in the rest of the body. Although heterogeneity of conductivity was observed in the tumor, the mean was still higher than the background.

Author List

Muftuler LT, Hamamura MJ, Birgul O, Nalcioglu O

Author

Lutfi Tugan Muftuler PhD Professor in the Neurosurgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Algorithms
Animals
Computers
Disease Models, Animal
Electric Impedance
Image Interpretation, Computer-Assisted
Magnetic Resonance Imaging
Neoplasms
Radiography
Rats
Software
Time Factors