Measurement of ion diffusion using magnetic resonance electrical impedance tomography. Phys Med Biol 2006 Jun 07;51(11):2753-62
Date
05/26/2006Pubmed ID
16723764DOI
10.1088/0031-9155/51/11/005Scopus ID
2-s2.0-33744824075 (requires institutional sign-in at Scopus site) 48 CitationsAbstract
In magnetic resonance electrical impedance tomography (MREIT), currents are applied to an object, the resulting magnetic flux density measured using MRI and the conductivity distribution reconstructed using these MRI data. In this study, we assess the ability of MREIT to monitor changes in the conductivity distribution of an agarose gel phantom, using injected current pulses of 900 microA. The phantom initially contained a distinct region of high sodium chloride concentration which diffused into the background over time. MREIT data were collected over a 12 h span, and conductivity images were reconstructed using the iterative sensitivity matrix method with Tikhonov regularization. The results indicate that MREIT was able to monitor the changing conductivity and concentration distributions resulting from the diffusion of ions within the agarose gel phantom.
Author List
Hamamura MJ, Muftuler LT, Birgul O, Nalcioglu OAuthor
Lutfi Tugan Muftuler PhD Professor in the Neurosurgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AlgorithmsDiffusion
Electric Conductivity
Electric Impedance
Humans
Image Processing, Computer-Assisted
Ions
Magnetic Resonance Imaging
Phantoms, Imaging
Reproducibility of Results
Sensitivity and Specificity
Sepharose
Sodium Chloride
Tomography, X-Ray Computed
