N-Tropic variants obtained after co-infection with N- and B-tropic murine leukemia viruses. J Virol 1976 Apr;18(1):324-31
Date
04/01/1976Pubmed ID
176467Pubmed Central ID
PMC515551DOI
10.1128/JVI.18.1.324-331.1976Scopus ID
2-s2.0-0017259424 (requires institutional sign-in at Scopus site) 12 CitationsAbstract
Sc-1 cells co-infected with small XC plaque-forming N-tropic and large XC plaque-forming B-tropic murine leukemia viruses produced, in addition to parental types, progeny with the phenotype, large XC plaque morphology, and N-tropism. This phenotype remained stable through end point titration and plaque purification on NIH/3T3 cells and growth on BALB/3T3 cells. These N-tropic viruses (XLP-N virus) grow to unusually high titer and make very large XC plaques.
Author List
Hopkins N, Traktman P, Whalen KMESH terms used to index this publication - Major topics in bold
AnimalsCell Line
Crosses, Genetic
Genetic Variation
Leukemia Virus, Murine
Mice
Mice, Inbred Strains
Species Specificity
Viral Plaque Assay
