Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Acute kidney injury requiring dialysis secondary to adenovirus nephritis in renal transplant recipient. Transpl Infect Dis 2011 Apr;13(2):174-7

Date

10/16/2010

Pubmed ID

20946204

DOI

10.1111/j.1399-3062.2010.00577.x

Scopus ID

2-s2.0-79953322013 (requires institutional sign-in at Scopus site)   31 Citations

Abstract

Disseminated adenoviral infection is a serious problem, especially in an immunocompromised host. The disease carries a mortality rate reaching as high as 80%. It is seen most frequently in bone marrow transplant recipients, where it causes pneumonia and disseminated disease. In solid organ transplant recipients it causes graft infection. We report the case of a renal transplant recipient with disseminated adenoviral infection and acute kidney failure requiring dialysis. Reduction of immunosuppression and 1 dose of cidofovir were associated with resolution of viremia and viruria and return of kidney function to near baseline.

Author List

Sujeet K, Vasudev B, Desai P, Bellizzi J, Novoa-Takara L, He C, El-Meanawy A

Authors

Ashraf El-Meanawy MD, PhD Professor in the Medicine department at Medical College of Wisconsin
Kumar Sujeet MD Staff Physician in the Medicine department at Medical College of Wisconsin
Brahm Vasudev MD Associate Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adenovirus Infections, Human
Aged
Antiviral Agents
Cytosine
Female
Humans
Kidney
Kidney Diseases
Kidney Transplantation
Nephritis
Organophosphonates
Time Factors