Medical College of Wisconsin
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Hypercoagulability in cancer. Hematol Oncol Clin North Am 1996 Apr;10(2):499-530

Date

04/01/1996

Pubmed ID

8707766

DOI

10.1016/s0889-8588(05)70349-x

Scopus ID

2-s2.0-0029980575 (requires institutional sign-in at Scopus site)   157 Citations

Abstract

The association of cancer with a hypercoagulable state is documented by numerous clinical, biochemical, pathologic, and pharmacologic studies. This association is manifested clinically by an increased incidence of intravascular thrombotic events in cancer patients and by fibrin deposition in and around tumor beds. Thromboembolic disease is a major cause of morbidity and mortality in patients with malignancy. This article discusses the complex pathogenesis of this problem and the associated laboratory and clinical syndromes with recommendations on diagnosis and treatment.

Author List

Green KB, Silverstein RL

Author

Roy L. Silverstein MD Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Blood Coagulation Disorders
Humans
Laboratories
Neoplasms
Neoplasms, Unknown Primary
Reference Values
Risk Factors
Syndrome
Thrombosis