Medical College of Wisconsin
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Hemophilia gene therapy: update. Curr Opin Hematol 2002 Sep;9(5):430-6

Date

08/13/2002

Pubmed ID

12172462

DOI

10.1097/00062752-200209000-00007

Scopus ID

2-s2.0-0036341573 (requires institutional sign-in at Scopus site)   10 Citations

Abstract

Gene transfer is an exciting and potentially important treatment approach for hemophilia A and B. Four phase I clinical trials of the safety of gene transfer in hemophilia A or B have been completed and two more trials are currently underway. The results of these trials indicate that gene transfer in hemophilia with the vectors and doses used is safe and well tolerated. Efforts continue to understand the basic biology and improve the efficiency of gene transfer.

Author List

Monahan PE, White GC 2nd

Author

Gilbert C. White MD Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Clinical Trials as Topic
Factor IX
Factor VIII
Genetic Therapy
Genetic Vectors
Hemophilia A
Hemophilia B
Humans