Improving adverse-drug-reaction reporting in ambulatory care clinics at a Veterans Affairs hospital. Am J Health Syst Pharm 2002 May 01;59(9):841-5
Date
05/15/2002Pubmed ID
12004462DOI
10.1093/ajhp/59.9.841Scopus ID
2-s2.0-0036569540 (requires institutional sign-in at Scopus site) 29 CitationsAbstract
The detection of adverse drug reactions (ADRs) by a traditional passive reporting system and by a method involving patient and provider interviews was studied. The study sample consisted of randomly selected outpatients seen by their primary care provider during scheduled appointments in January and February 2001 at a Veterans Affairs medical center. After ambulatory care clinic sessions, patients and providers were asked (by telephone and in person, respectively) to identify potential ADRs. Also obtained were demographic data, information about drug regimens, and the severity and management of each ADR. A standardized ADR-assessment tool was used to determine the severity of each reported reaction and its causal relationship with the medication. A total of 198 patients were included. Of these, 51 (26%) had one or more ADRs. The patient and provider interviews identified a total of 83 ADRs, compared with 1 ADR identified by the passive reporting system. When providers were made aware of the ADRs they had not identified, changes were made to the patient's medication regimen in 34% of cases. The risk of an ADR was not associated with age, number of medications, or provider type. Direct patient and provider interviews yielded a significantly higher rate of ADR detection in an ambulatory care setting than did a passive ADR-reporting system.
Author List
Aspinall MB, Whittle J, Aspinall SL, Maher RL Jr, Good CBAuthor
Jeffrey Whittle MD Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Adverse Drug Reaction Reporting SystemsAged
Data Collection
Female
Hospitals, Veterans
Humans
Interviews as Topic
Male
Middle Aged
Outpatient Clinics, Hospital
Outpatients
Pharmacy Service, Hospital
Random Allocation
United States
United States Department of Veterans Affairs
