Medical College of Wisconsin
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Radium in Wisconsin drinking water: an analysis of osteosarcoma risk. Arch Environ Health 2002;57(4):294-303

Date

01/18/2003

Pubmed ID

12530595

DOI

10.1080/00039890209601412

Scopus ID

2-s2.0-0036664565 (requires institutional sign-in at Scopus site)   18 Citations

Abstract

Epidemiological studies of radium dial painters have found an association between exposure to high-dose radium and bone cancers. However, only limited data exist on the relationship between low doses of radium, as are found in some drinking water sources, and osteosarcoma. The authors conducted a population-based case-control study to examine the association between exposure to radium in drinking water and the occurrence of osteosarcoma. Estimates of radium exposure and covariates used were based on subjects' residential ZIP codes. The median radium level was not significantly associated with osteosarcoma (odds ratio = .98; 95% confidence interval = .93, 1.04; p = .56). The authors found no evidence that radium, at current levels in Wisconsin drinking water, resulted in excess cases of osteosarcoma.

Author List

Guse CE, Marbella AM, George V, Layde PM



MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Aged
Bone Neoplasms
Case-Control Studies
Child
Child, Preschool
Female
Humans
Infant
Infant, Newborn
Male
Middle Aged
Odds Ratio
Osteosarcoma
Radium
Registries
Risk Assessment
Water Supply
Wisconsin