Use of polylactide resorbable film as an adhesion barrier. Orthopedics 2002 Oct;25(10 Suppl):s1121-30
Date
10/29/2002Pubmed ID
12401022DOI
10.3928/0147-7447-20021002-02Scopus ID
2-s2.0-0036805260 (requires institutional sign-in at Scopus site) 18 CitationsAbstract
The present investigation evaluates two thicknesses of a resorbable polylactide barrier film as an adhesion barrier to posterior spine scar formation. A readily contourable, thin film was placed directly over the dura. The thick film was placed above the lamina defect to act as a physical barrier inhibiting the prolapse of soft tissue into the epidural space. Through a combination of gross dissection with and without scar scores, quantitative analysis of collagen adjacent to the scar site, and histologic evaluation, the resorbable adhesion barrier membranes were found to be effective treatment for reduction of posterior adhesions. The gross dissection demonstrated that both thicknesses of resorbable polymer barrier films created a controlled dissection plane, facilitated access to the epidural space, and provided a reduction in the tissue adhered to the dura.
Author List
Welch WC, Cornwall GB, Toth JM, Turner AS, Thomas KA, Gerszten PC, Nemoto EMAuthor
Jeffrey M. Toth PhD Associate Dean for Research in the School of Dentistry department at Marquette UniversityMESH terms used to index this publication - Major topics in bold
Absorbable ImplantsAnimals
Biocompatible Materials
Cicatrix
Disease Models, Animal
Dogs
Intervertebral Disc Displacement
Laminectomy
Materials Testing
Polyesters
Postoperative Complications
Probability
Reference Values
Sensitivity and Specificity
Sheep
Statistics, Nonparametric
Tissue Adhesions
