Bidirectional ventricular tachycardia and channelopathy. Am J Cardiol 2003 Oct 15;92(8):991-5
Date
10/15/2003Pubmed ID
14556882DOI
10.1016/s0002-9149(03)00987-1Scopus ID
2-s2.0-0141817952 (requires institutional sign-in at Scopus site) 8 CitationsAbstract
Based on similarity of electrocardiographic features, bidirectional ventricular tachycardia has been considered a variant of long QT syndrome. Genes causing long QT syndrome were used as candidate genes in 4 patients with bidirectional ventricular tachycardia. In 2 patients, we identified a common low penetrance HERG allele (R1047L) with an intermediate biophysical phenotype.
Author List
Laohakunakorn P, Benson DW, Yang P, Yang T, Roden DM, Kugler JDMESH terms used to index this publication - Major topics in bold
AdolescentAlleles
Cation Transport Proteins
Child, Preschool
DNA-Binding Proteins
ERG1 Potassium Channel
Electrophysiologic Techniques, Cardiac
Ether-A-Go-Go Potassium Channels
Female
Humans
Long QT Syndrome
Male
Phenotype
Potassium Channels
Potassium Channels, Voltage-Gated
Sodium Channels
Tachycardia, Ventricular
Trans-Activators
Transcriptional Regulator ERG
