Faculty Collaboration Database

Comparison of single versus multidose blood cardioplegia in arterial switch procedures. Ann Thorac Surg 1988 May;45(5):548-53

Date

05/01/1988

Pubmed ID

3365046

DOI

10.1016/s0003-4975(10)64530-4

Scopus ID

2-s2.0-0023907491 (requires institutional sign-in at Scopus site)   16 Citations

Abstract

Fifty-three patients with transposition of the great arteries and Taussig-Bing anomaly undergoing an arterial switch procedure were divided into two groups. Group 1 (N = 32) received multidose cardioplegia injected initially into the aortic root and subsequently into the coronary artery orifices and Group 2 (N = 21), single-dose cardioplegia injected into the aortic root. The mean aortic cross-clamp and bypass times were generally longer in Group 1 compared with Group 2. Group 1 patients with simple transposition undergoing primary repair (N = 15) had an aortic cross-clamp time of 80 +/- 8 minutes and a bypass time of 203 +/- 27 minutes versus 64 +/- 6 minutes (p less than 0.001) and 170 +/- 15 minutes (p less than 0.01), respectively, for similar patients in Group 2 (N = 10). Group 1 patients with simple transposition undergoing staged repair (N = 7) had an aortic cross-clamp time of 71 +/- 6 minutes and a bypass time of 201 +/- 24 minutes versus 66 +/- 4 minutes (p = not significant [NS]) and 226 +/- 25 minutes (p = NS), respectively, for Group 2 (N = 6). In Group 1 patients with complex transposition (N = 10), the aortic bypass time was 79 +/- 12 minutes and the bypass time was 261 +/- 40 minutes versus 64 +/- 11 minutes (p less than 0.05) and 225 +/- 16 minutes (p less than 0.1), respectively, for Group 2 (N = 5). Early mortality was 16% (5/32) in Group 1; there were no early deaths in Group 2.(ABSTRACT TRUNCATED AT 250 WORDS)

Author List

DeLeon SY, Idriss FS, Ilbawi MN, Duffy CE, Benson DW Jr, Backer CL

MESH terms used to index this publication - Major topics in bold

Aorta
Cardioplegic Solutions
Child, Preschool
Constriction
Echocardiography
Electrocardiography
Follow-Up Studies
Humans
Infant
Infant, Newborn
Injections, Intra-Arterial
Postoperative Complications
Time Factors
Transposition of Great Vessels