Psychological adjustment, knowledge and unmet information needs in women undergoing PGD. Hum Reprod 2010 Jun;25(6):1481-9
Date
04/13/2010Pubmed ID
20382972DOI
10.1093/humrep/deq086Scopus ID
2-s2.0-77952854149 (requires institutional sign-in at Scopus site) 17 CitationsAbstract
BACKGROUND: Women often enter preimplantation genetic diagnosis (PGD) treatment following traumatic reproductive and genetic histories, the detrimental psychological effects of which are known to be long lasting in some cases. In addition, attempting IVF with PGD requires an in-depth understanding of the aspects of the technology. The level of information that is required and retained by women entering treatment is important for clinicians to understand. To date, neither of these issues has been explored empirically. To address this, we assessed mood and information-seeking behavior in a sample of women entering PGD.
METHODS: Fifty women entering PGD treatment completed self-administered questionnaires that assessed anxiety, depression, knowledge of technical aspects of PGD, expectancy of establishing a pregnancy and unmet information needs.
RESULTS: Anxiety and depression rates were similar to normal population data. State anxiety was associated with degree of financial worry [beta = 0.36, t = 2.60, P = 0.01, 95% confidence interval (CI): 0.03-0.23], and living in an inner metropolitan area (beta = 0.30, P = 0.03, 95% CI: 0.32-10.81). Unmet information needs were positively associated with women's education (beta = 0.97, P = 0.01, 95% CI: 0.22-1.73). Lastly, expectancy of establishing a pregnancy was above that of what clinicians provide as realistic PGD pregnancy chances and, unexpectedly, was also associated with degree of financial worry (beta = 0.36, P = 0.01, 95% CI: 0.07-0.56).
CONCLUSIONS: Women entering PGD are emotionally well adjusted although the financial costs associated with PGD are associated with increases in anxiety. The study is limited by its small sample size and the fact that partners were not assessed.
Author List
Karatas JC, Barlow-Stewart K, Meiser B, McMahon C, Strong KA, Hill W, Roberts C, Kelly PMESH terms used to index this publication - Major topics in bold
Adaptation, PsychologicalAffect
Anxiety
Depression
Female
Genetic Counseling
Health Knowledge, Attitudes, Practice
Health Services Needs and Demand
Humans
Infertility, Female
Information Seeking Behavior
Linear Models
Pregnancy
Preimplantation Diagnosis
Prenatal Diagnosis
Social Support
Socioeconomic Factors
Stress, Psychological
Surveys and Questionnaires
