Urothelial carcinoma recurrence in ileal orthotopic neobladder: urethrectomy and creation of ileal conduit. Urology 2007 Jan;69(1):184.e11-3
Date
02/03/2007Pubmed ID
17270649DOI
10.1016/j.urology.2006.10.013Scopus ID
2-s2.0-33846466463 (requires institutional sign-in at Scopus site) 10 CitationsAbstract
A patient who had previously undergone radical cystoprostatectomy and ileal neobladder with the Studer technique presented with a recurrence of urothelial carcinoma in the neobladder and urethra. Surgical treatment consisted of resection of the neobladder, urethrectomy, and creation of an ileal conduit using a separately isolated segment of ileum. Pathologic analysis revealed high-grade urothelial carcinoma implants to the Studer pouch and urethra, with spread to the mesenteric lymph nodes draining the pouch. Intraluminal tumor cell seeding appears to be an important mechanism of metachronous transitional cell carcinoma recurrence in the urethra and ileal mucosa of a neobladder.
Author List
Moore CD, Iczkowski KA, Blue KM, Algood CBMESH terms used to index this publication - Major topics in bold
Carcinoma, Transitional CellHumans
Ileum
Male
Middle Aged
Neoplasm Recurrence, Local
Urethra
Urinary Bladder Neoplasms
Urinary Diversion
Urinary Reservoirs, Continent
