Minimal criteria for the diagnosis of prostate cancer on needle biopsy. Ann Diagn Pathol 1997 Dec;1(2):104-29
Date
12/31/1998Pubmed ID
9869832DOI
10.1016/s1092-9134(97)80015-9Scopus ID
2-s2.0-0031292944 (requires institutional sign-in at Scopus site) 19 CitationsAbstract
Increased clinical screening of men at risk for prostate cancer, and the realization of the benefits of performing multiple biopsies per prostate, have facilitated early detection of malignancy, while presenting the pathologist with a growing array of diagnostic findings. Interpretation of these findings requires discussion of the minimal criteria required for the diagnosis of cancer on needle biopsy within a wide spectrum of related histologic findings. This spectrum includes small acinar proliferations suspicious for but not diagnostic of cancer, benign mimics of cancer, the preinvasive entity of high-grade prostatic intraepithelial neoplasia, and various treatment effects. Clinical implications of these findings and other prognostic factors are detailed.
Author List
Bostwick DG, Iczkowski KAMESH terms used to index this publication - Major topics in bold
AdenocarcinomaBiomarkers, Tumor
Biopsy, Needle
DNA, Neoplasm
Diagnosis, Differential
Humans
Image Processing, Computer-Assisted
Male
Ploidies
Prognosis
Prostatic Hyperplasia
Prostatic Intraepithelial Neoplasia
Prostatic Neoplasms
