Growth in children with Helicobacter pylori infection and dyspepsia. Arch Dis Child 2005 Oct;90(10):1025-8
Date
06/16/2005Pubmed ID
15956048Pubmed Central ID
PMC1720122DOI
10.1136/adc.2004.066803Scopus ID
2-s2.0-26044461989 (requires institutional sign-in at Scopus site) 48 CitationsAbstract
AIMS: To compare the height, weight, and body mass index (BMI) of children presenting with dyspeptic symptoms and Helicobacter pylori infection, to those with dyspepsia but without the infection.
METHODS: A retrospective chart review of 257 children was performed. 13C urea breath test was performed to detect H pylori infection; weight and height were recorded and BMI was calculated. Weight, height, and BMI SD scores were determined using the 1990 UK normative data. The Index of Multiple Deprivation 2004 (IMD 2004) scores, which measure deprivation at small area level, were calculated from the patients' postcodes.
RESULTS: Ninety seven of the 257 children were H pylori positive. The mean age at diagnosis and presenting symptoms of H pylori positive and negative patients were similar. The mean IMD 2004 scores for children with H pylori infection were significantly higher compared to H pylori negative patients, suggesting that children with the infection came from relatively more deprived areas. The mean weight and height SD score were significantly lower for children with H pylori infection compared to those without. However, this difference was no longer significant after adjusting for socioeconomic deprivation and ethnic differences between the groups.
CONCLUSION: Children with dyspepsia and H pylori infection were shorter and lighter than patients with similar symptoms but no infection. The differences in anthropometry may be due to socioeconomic and ethnic factors rather than H pylori infection.
Author List
Sood MR, Joshi S, Akobeng AK, Mitchell J, Thomas AGMESH terms used to index this publication - Major topics in bold
AdolescentAsia, Southeastern
Body Height
Body Mass Index
Body Weight
Chi-Square Distribution
Child
Dyspepsia
Female
Helicobacter Infections
Helicobacter pylori
Humans
Linear Models
Male
Poverty
Retrospective Studies
Socioeconomic Factors
