Sympathetic neuropathy and dysphagia following doxycycline sclerotherapy. Int J Pediatr Otorhinolaryngol 2013 Sep;77(9):1613-6
Date
08/13/2013Pubmed ID
23931985DOI
10.1016/j.ijporl.2013.07.005Scopus ID
2-s2.0-84882701945 (requires institutional sign-in at Scopus site) 8 CitationsAbstract
This case report demonstrates neurologic sequela following treatment with doxycycline sclerotherapy. A six-week-old child presented with respiratory distress from a macrocystic lymphatic malformation, extending from the skull base to the anterior mediastinum. Following doxycycline sclerotherapy, the airway symptoms resolved; however, the child developed silent aspiration and Horner's syndrome. Two months following treatment the patient resumed oral diet and at one year post-intervention there has been no recurrence of symptoms, with only mild ptosis remaining. While neuropathies following doxycycline sclerotherapy have been described, aspiration has never been documented. This case demonstrates a single patient's clinical course and resolution of their neuropathies.
Author List
Wang KL, Chun RH, Kerschner JE, Sulman CGAuthor
Robert H. Chun MD Professor in the Otolaryngology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Airway ObstructionDeglutition Disorders
Doxycycline
Female
Follow-Up Studies
Horner Syndrome
Humans
Infant
Lymphatic Abnormalities
Magnetic Resonance Imaging
Respiratory Aspiration
Respiratory Distress Syndrome, Newborn
Risk Assessment
Sclerotherapy