Faculty Collaboration Database

Leukocyte trafficking in free-flowing cerebrospinal fluid of normal rhesus macaques (Macaca mulatta). J Med Primatol 1996 Jan;25(1):8-13

Date

01/01/1996

Pubmed ID

8740946

DOI

10.1111/j.1600-0684.1996.tb00186.x

Scopus ID

2-s2.0-0029716222 (requires institutional sign-in at Scopus site)   4 Citations

Abstract

Cellular components in free-flowing cerebrospinal fluid (CSF) of normal rhesus macaques were characterized. Microscopic counting enumerated the total number of leukocytes, percentage of polymorphonuclear cells (PMN), leukocytes with nonspecific esterase (NSE), and those reducing nitro blue tetrazolium (NBT). Flow cytometric analysis further identified CD4, CD8, CD14, and CD20 positive leukocytes. These experiments established reliable techniques for evaluating cellular components in CSF from rhesus macaques and documented the difference in the CD4/CD8 ratio between peripheral blood (PB) and CSF compartments under normal physiological conditions.

Author List

Hou FY, Coe CL, Erickson C

Author

Fang Yao Stephen Hou PhD, MB(ASCP)QCYM, MLS(ASCPi) Clinical Assistant Professor in the Biomedical Sciences Laboratory Programs department at University of Wisconsin - Milwaukee

MESH terms used to index this publication - Major topics in bold

Animals
Antigens, CD20
Biomarkers
CD4 Antigens
CD4-CD8 Ratio
CD8 Antigens
Carboxylesterase
Carboxylic Ester Hydrolases
Cerebrospinal Fluid
Flow Cytometry
Leukocytes
Lipopolysaccharide Receptors
Macaca mulatta
Neutrophils
T-Lymphocytes