The cost of self-imposed regulatory burden in animal research. FASEB J 2014 Aug;28(8):3297-300
Date
05/03/2014Pubmed ID
24784580DOI
10.1096/fj.14-254094Scopus ID
2-s2.0-84905216344 (requires institutional sign-in at Scopus site) 15 CitationsAbstract
U.S. federal regulations and standards governing the care and use of research animals enacted in the mid- to late 1980s, while having positive effects on the welfare and quality of the animals, have resulted in dramatic increases in overall research costs. In addition to the expenses of housing and caring for animals according to the standards, establishing the requisite internal compliance bureaucracies has markedly driven up costs, in both institutional monetary expenditures and lost research effort. However, many institutions are increasing these costs even further through additional self-imposed regulatory burden, typically characterized by overly complex compliance organizations and unnecessary policies and procedures. We discuss the sources of this self-imposed burden and recommend strategies for avoiding it while preserving an appropriate focus on animal well-being and research success.
Author List
Thulin JD, Bradfield JF, Bergdall VK, Conour LA, Grady AW, Hickman DL, Norton JN, Wallace JMMESH terms used to index this publication - Major topics in bold
Academies and InstitutesAnimal Care Committees
Animal Experimentation
Animal Testing Alternatives
Animal Welfare
Animals
Animals, Laboratory
Conflict of Interest
Cost-Benefit Analysis
Costs and Cost Analysis
Forms and Records Control
Guideline Adherence
Guidelines as Topic
Housing, Animal
Organizational Policy
Research
