Determinants of dialyzer reuseability. ASAIO Trans 1991;37(3):M185-6
Date
07/01/1991Pubmed ID
1751103Scopus ID
2-s2.0-0026183272 (requires institutional sign-in at Scopus site) 1 CitationAbstract
The authors observed a wide variability in the number of uses per dialyzer in their hemodialysis patients. In 54 patients who reused their dialyzers, heparin dose (U/kg/min) related directly and white blood cell count related inversely to reuseability. Average reuse was 5.1 +/- 2.9 (SD) in diabetics (n = 13) and 7.8 +/- 3.8 (SD) in non-diabetics (n = 41; p = 0.007). Of the diabetics, 77% achieved six or less reuses, and 59% of non-diabetics achieved six or more reuses (chi-square = 4.96; p less than 0.05). In non-diabetics, heparin dose was the most significant determinant of reuse, and in diabetics the major determinant was white blood cell count. Hematocrit levels, platelet count, erythropoietin use, or type of membrane (polysulfone/cellulose acetate) did not correlate with reuseability. It was concluded that reuseability of dialyzers is less in diabetic patients, patients on lower heparin doses (U/kg/min), and patients with higher white blood cell counts. Determinants of dialyzer reuseability warrant further study.
Author List
Sievers SG, Stack JL, Piering WF, Cohen EPMESH terms used to index this publication - Major topics in bold
Blood Chemical AnalysisDiabetic Nephropathies
Equipment Contamination
Equipment Safety
Heparin
Humans
Kidney Failure, Chronic
Kidneys, Artificial
Leukocyte Count
Membranes, Artificial
Risk Factors
Thrombosis
