Recent molecular and cellular advances in pediatric bone marrow transplantation. Pediatr Clin North Am 2006 Aug;53(4):685-98
Date
07/29/2006Pubmed ID
16872999DOI
10.1016/j.pcl.2006.05.007Scopus ID
2-s2.0-33746253782 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
The field of allogeneic transplantation has made vast improvements since its inception in 1968. Improvements in supportive care have greatly improved survival. Delayed immune reconstitution, graft versus host disease, and relapse of disease still pose great obstacles. This article has highlighted novel strategies for using cellular therapy in conjunction with hematopoietic cell transplantation (HCT) that potentially may lead to improved clinical outcomes for patients undergoing HCT in the future.
Author List
Talano JA, Margolis DAAuthors
David A. Margolis MD Chair, Professor in the Pediatrics department at Medical College of WisconsinJulie-An M. Talano MD Professor in the Pediatrics department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
DNA Virus InfectionsGraft vs Host Disease
Graft vs Leukemia Effect
Hematopoietic Stem Cell Transplantation
Humans
Immunotherapy
Leukocyte Transfusion
Neoplasms
Pediatrics
T-Lymphocytes
Virus Diseases