Medical College of Wisconsin
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Turnover of mouse photoreceptor outer segments in constant light and darkness. Invest Ophthalmol Vis Sci 1979 Oct;18(10):1019-24

Date

10/01/1979

Pubmed ID

478775

Scopus ID

2-s2.0-0018306891 (requires institutional sign-in at Scopus site)   87 Citations

Abstract

Pigmented mice differ from frogs in that lighting regime has only a small effect on rod outer segment turnover. During 8 days in constant light or darkness, disc addition measured as total displacement of a radioactive band in rod outer segments of mice which has received injections of tritiated amino acids was never modified by more than 7% compared to cyclic light controls. Disc shedding continued in each lighting regime, and as judged from outer segment dimensions, disc shedding approximately balanced disc addition.

Author List

Besharse JC, Hollyfield JG

Author

Joseph C. Besharse PhD, MA Emeritus Professor in the Cell Biology Neurobiology and Anatomy department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Autoradiography
Darkness
Leucine
Light
Male
Mice
Mice, Inbred C57BL
Optic Disk
Phagocytes
Phenylalanine
Photic Stimulation
Photoreceptor Cells
Tritium