Medical College of Wisconsin
CTSIResearch InformaticsREDCap

The medical ethics of bone marrow transplantation in childhood. J Pediatr 1975 Jan;86(1):145-50

Date

01/01/1975

Pubmed ID

1089140

DOI

10.1016/s0022-3476(75)80728-1

Scopus ID

2-s2.0-0016426815 (requires institutional sign-in at Scopus site)   21 Citations

Abstract

Bone marrow transplantation has been utilized for the treatment of severe aplastic anemia in a program at The Children's Hospital Medical Center. A protocol has been developed to help ensure that the interests and rightful claims of all involved parties will be taken into account. Three cases are presented. In one case all involved parties concurred with the plan for bone marrow transplantation. In a second case the prospective donor was deemed mentally incompetent to give truly informed consent for the procedure. In a third case the parents were unwilling to have their child undergo transplantation. The ethical issues raised in these cases suggest the need for further development of a moral technology to enhance decision-making competence and to aid in the recognition and application of the rights of children without impeding the advancement of pediatric medicine.

Author List

Levine MD, Camitta BM, Nathan D, Curran WJ



MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Anemia, Aplastic
Bone Marrow Cells
Bone Marrow Transplantation
Boston
Child
Child, Preschool
Ethics, Medical
Humans
Informed Consent
Jurisprudence
Male
Mental Disorders
Peer Review
Tissue Donors
Transplantation, Homologous