Increasing antiretroviral drug access for children with HIV infection. Pediatrics 2007 Apr;119(4):838-45
Date
04/04/2007Pubmed ID
17403860DOI
10.1542/peds.2007-0273Scopus ID
2-s2.0-34147135104 (requires institutional sign-in at Scopus site) 76 CitationsAbstract
Although there have been great gains in the prevention of pediatric HIV infection and provision of antiretroviral therapy for children with HIV infection in resource-rich countries, many barriers remain to scaling up HIV prevention and treatment for children in resource-limited areas of the world. Appropriate testing technologies need to be made more widely available to identify HIV infection in infants. Training of practitioners in the skills required to care for children with HIV infection is required to increase the number of children receiving antiretroviral therapy. Lack of availability of appropriate antiretroviral drug formulations that are easily usable and inexpensive is a major impediment to optimal care for children with HIV. The time and energy spent trying to develop liquid antiretroviral formulations might be better used in the manufacture of smaller pill sizes or crushable tablets, which are easier to dispense, transport, store, and administer to children.
Author List
American Academy of Pediatrics Committee on Pediatric AIDS, Section on International Child Health, Havens PL, Gibb DMMESH terms used to index this publication - Major topics in bold
AdolescentAnti-Retroviral Agents
Antiretroviral Therapy, Highly Active
Chemistry, Pharmaceutical
Child
Child Health Services
Child Welfare
Child, Preschool
Developing Countries
Drug Utilization
Female
Global Health
HIV Infections
Health Planning Guidelines
Humans
Infant
Infant, Newborn
Infectious Disease Transmission, Vertical
International Cooperation
Male
Policy Making
Pregnancy
Pregnancy Complications, Infectious
Risk Factors
Socioeconomic Factors
World Health Organization
