Faculty Collaboration Database

Foveal contour changes following surgery for idiopathic epiretinal membrane. Invest Ophthalmol Vis Sci 2014 Nov 13;55(12):7754-60

Date

11/15/2014

Pubmed ID

25395487

Pubmed Central ID

PMC4541481

DOI

10.1167/iovs.14-15075

Scopus ID

2-s2.0-84915755758 (requires institutional sign-in at Scopus site)   33 Citations

Abstract

PURPOSE: We evaluated the change in foveal contour in eyes with idiopathic epiretinal membrane (ERM) before and four months following pars plana vitrectomy with internal limiting and epiretinal membrane peeling, and correlated foveal contour with best corrected visual acuity (BCVA) and optical coherence tomography (OCT) parameters.

METHODS: Retrospective chart review of consecutive patients undergoing surgery with pre- and postoperative OCT. Foveal contour grading was devised according to the thickness of the fovea relative to the surrounding macula from OCT radial line scans: Grade 0, foveal depression relative to surrounding macula; Grade 1, relative flatness; and Grade 2, fovea thicker than surrounding macula. Baseline and follow-up grades were compared for change and correlated with BCVA, central retinal thickness (CRT), central subfield thickness (CST), central subfield volume (CSV), and integrity of the ellipsoid zone (EZ).

RESULTS: Among 41 eyes of 41 patients, mean follow-up was 125 days. No eyes were Grade 0 at baseline; 7 of 41 eyes were Grade 0 at follow-up. Baseline Grade 1 eyes improved CRT (P < 0.001), CST (P < 0.001), CSV (P = 0.002), and BCVA (P = 0.022). Baseline Grade 2 eyes improved CRT (P < 0.001), CST (P < 0.001), and CSV (P < 0.001), but not BCVA (P = 0.369).

CONCLUSIONS: We developed a novel foveal contour grading method to assess retinal contour in ERM eyes before and after surgery. In eyes with ERM and no foveal depression, the majority did not regain foveal depression following surgery even though retinal thickness improved.

Author List

Mathews NR, Tarima S, Kim DG, Kim JE

MESH terms used to index this publication - Major topics in bold

Aged
Basement Membrane
Epiretinal Membrane
Female
Follow-Up Studies
Fovea Centralis
Humans
Male
Middle Aged
Retrospective Studies
Tomography, Optical Coherence
Visual Acuity
Vitrectomy